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Skip to Search Results- 3Membrane protein
- 1Amphipathic polymers
- 1Corneal dystrophies CHED FECD
- 1ER retention and protein misfolding
- 1Lipids
- 1NHE1
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An NMR-based approach to the structural and functional investigation of the Na+/H+ exchanger NHE1
DownloadFall 2013
The Na+/H+ exchanger isoform 1 (NHE1) is the predominant isoform in mammalian cells, and regulates intracellular pH and ion concentrations. NHE1 also interacts with numerous proteins and signalling pathways. Consequently, it has been found to influence cell volume, growth, differentiation, and...
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Polymer-Based Nanodiscs for Structural and Functional Analyses of Bacterial and Mammalian Membrane Proteins
DownloadSpring 2020
Unlike cytosolic proteins, membrane proteins (MPs) are embedded within the plasma membrane and the lipid bilayer of intracellular organelles. MPs serve in various cellular processes such as ion and metabolite transports, bioenergetic processes, signal transductions, and cell-cell communications....
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Fall 2015
Congenital hereditary endothelial corneal dystrophy type 2 (CHED2), Harboyan Syndrome (HS) and Fuchs endothelial corneal dystrophy (FECD) are caused by SLC4A11 mutations. The majority of SLC4A11 point mutations cause SLC4A11 misfolding and retention in the endoplasmic reticulum (ER). This impairs...