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Development and Characterization of New Stationary Phases for Hydrophilic Interaction Liquid Chromatography
DownloadSpring 2014
Ibrahim, Mohammed Elsayed Abdelatif
Hydrophilic interaction liquid chromatography (HILIC) has gained high popularity among separation scientists in the last two decades due to its ability to retain polar analytes. Many new HILIC stationary phases with different selectivities have appeared in the recent literature. Such developments...
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Spring 2016
The analysis of thousands of metabolites and lipids for discovery of metabolite biomarkers for disease monitoring and diagnosis requires the highest sensitivity and robust methods. Metabolomics is the study of metabolites found in the body, which can be used to discover biomarkers of disease or...
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In-line Ozonolysis coupled to Mass Spectrometry- A New Dimension of Structural Determination for Lipids
DownloadFall 2014
The location of double bonds within unsaturated lipids can greatly affect their biological functions. Liquid chromatography coupled to mass spectrometry (LC/MS) has become a powerful tool for lipid separation and structural elucidation. However, the determination of double bond position remains...
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Theoretical understanding and method development for high performance liquid chromatography-mass spectrometry for environmental analysis
DownloadFall 2021
Method development is a fundamental key step for effective and efficient analytical separations and analyses. Of particular importance is method development for high performance liquid chromatography-mass spectrometry (HPLC-MS). Specifically, environmental analysis applications require dedicated...