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- 2Cardiac hypertrophy
- 2Hypertension
- 1Angiotensin II
- 1Cardaic fibrosis
- 1Cardiac fibrosis
- 1Hypertensive cardiac remodelling
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Spring 2011
Angiotensin II signals cardiovascular disease through metalloproteinases including MMP-2, MMP-7 and ADAM-17/TACE. We hypothesized that these metalloproteinases regulate each other at the transcriptional level. Further, MMP-2, being a major gelatinase in cardiac and vascular tissue, could mediate...
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Fall 2013
Despite many decades of research and drug development, the diseases of the cardiovascular system remain a major health threat in the modern world. Hypertensive cardiac disease is a cardiovascular condition characterized by the co-occurrence of hypertension and pathological cardiac remodeling...
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