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Skip to Search Results- 2Al Sayah, Fatima
- 1Achtymichuk, Karly A
- 1Adame Perez, Stephany
- 1Al-Adra, David P.
- 1Albalawi, Zaina H
- 1Anderson, Sarah J
- 7Department of Agricultural, Food, and Nutritional Science
- 5Department of Surgery
- 5School of Public Health
- 3Faculty of Pharmacy and Pharmaceutical Sciences
- 3School Public Health Sciences
- 2Department of Medical Microbiology and Immunology
- 2Eurich, Dean (School of Public Health)
- 2Johnson, Jeff A. (School of Public Health Sciences, University of Alberta)
- 2Williams, Beverly (Faculty of Nursing, University of Alberta)
- 1Al Hamarneh, Yazid (Pharmacology)
- 1Anderson, Colin (Medical Microbiology and Immunology and Surgery)
- 1Baldwin, Troy (Medical Microbiology and Immunology)
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Drug Exposure Definition and Healthy User Bias Impacts on the Evaluation of Oral Anti Hyperglycemic Therapies
DownloadFall 2017
Accurate estimation of medication use is an essential component of any pharmacoepidemiological research as exposure misclassification will threaten study validity and lead to spurious associations. Many pharmacoepidemiological studies use simple definitions, such as the categorical “any versus no...
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The impact of diabetic foot problems on health-related quality of life of people with diabetes
DownloadSpring 2017
People with diabetes are at a greater risk of developing foot complications and this chronic condition continues to be the leading cause of non-traumatic amputations in Canada. The purpose of this thesis was to examine the impact diabetic foot problems have on health-related quality of life of...
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Fall 2016
Seniors requiring advanced care and supports are often residing in residential care facilities (RCF). Although, up to 33% of the residents are living with known diabetes, administrators and clinicians are faced with two important questions: 1) what is the prevalence of undetected diabetes; and,...
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Spring 2016
Living with diabetes is challenging. Achieving optimal blood sugar balance involves major lifestyle choices and changes that can be difficult to sustain over time. When a woman with diabetes immigrates to a new country with very different social and cultural customs, religion, values, norms, and...
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Contributions of Bim and Nur77 to multiple mechanisms of T cell tolerance following high affinity antigen encounter
DownloadSpring 2015
Prevention of autoimmune disease requires the elimination or inactivation of T cells that are highly reactive to self-peptides. During T cell development in the thymus, self-reactive thymocytes undergo negative selection upon receiving a high affinity T cell receptor (TCR) signal following...
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Fall 2015
The development of the Edmonton protocol was an important milestone in the process of establishing islet transplantation as a cure for diabetes. However, many challenges must still be overcome, including the shortage of donor organs. To address this issue, we believe that neonatal porcine islets...
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Influenza Vaccination in Patients with Diabetes: Exploration of the Healthy User in Pharmacoepidemiology Studies
DownloadFall 2015
Pharmacoepidemiologic studies of preventive medications or therapies are prone to the healthy user bias, as patients who are prescribed and adhere to preventive medications/therapies are likely different than patients not receiving these medications in multiple aspects of their lives. These...
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Long-term Impacts of Early Life Antibiotic Exposure on Intestinal Microbiota and Metabolic Disease
DownloadFall 2015
Although genetic factors, diet choices and sedentary lifestyle have long been considered main risk contributors for obesity and diabetes mellitus, years of study show that these factors cannot fully explain the increasing rate of worldwide metabolic disease. Epidemiological studies in recent...
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Spring 2015
Background: Diabetes and chronic kidney disease are two leading public health concerns. Patients with both diabetes and chronic kidney disease may be at elevated risk for suboptimal nutrient status due to diet restrictions, electrolyte and fluid imbalance, and altered metabolism. Objectives: The...
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Mechanisms of Pharmacists Interventions on Medication Management and Adherence in Patients with Type 2 Diabetes
DownloadSpring 2014
Optimal management of type 2 diabetes requires a collaborative, team-based approach; however, the role of pharmacists on these teams has not been well-defined. In the first study of this thesis, a systematic review examined components of pharmacist interventions to improve adherence to oral...