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An exploration of neural network activity within the limb-associated somatosensory cortex of the healthy and stroke injured brain of mice
DownloadFall 2022
Altered somatosensation is a hallmark of incomplete recovery from stroke. Although the basic mechanisms of limb-associated somatosensation have been well studied in primates, comparatively little literature exists on the limb-associated somatosensory system of rodents. Rodent models are the...
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Central nervous system plasticity associated with pain in a mouse model of multiple sclerosis, and the antinociceptive effects of the antidepressant phenelzine
DownloadFall 2017
Multiple sclerosis (MS) is a chronic, progressive disease that involves neuroinflammation, demyelination, and neurodegeneration within the central nervous system (CNS). While loss of motor function and paralysis are considered the primary clinical consequences of MS, the disease is also...
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Fall 2023
The overarching idea of this thesis stemmed from previous work in our lab, where it was noticed that females and males exhibited different disease trajectories in a model of Multiple Sclerosis. Combined with our observation of different outcome metrics for peripheral nociception suggested that...