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High throughput genotyping of single nucleotide polymorphisms in the Plasmodium falciparum dhfr and dhps genes by asymmetric PCR and melt-curve analysis
DownloadFall 2011
Mutations within Plasmodium falciparum dihydrofolate reductase (pfdhfr) and dihydropteroate synthase (pfdhps) genes contribute to resistance to antimalarials such as sulfadoxine-pyrimethamine (SP). Single nucleotide polymorphisms (SNPs) within codons 51, 59, 108 and 164 in the pfdhfr gene and...
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Spring 2012
Immigrant-receiving countries like Canada must meet the challenge of tuberculosis (TB) in their foreign-born populations. One puzzling question is why, despite fluctuating levels of immigration from high incidence source countries, only modest variations in foreign-born TB incidence have been...