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Reflections on the Cost of "Low-Cost" Whole Genome Sequencing: Framing the Health Policy Debate
Download2014-10-24
Miller, Fiona A., Hogarth, Stuart, Evans, Jim, McCabe, Christopher, Pullman, Daryl, Joly, Yann, Szego, Michael J., Bubela, Tania, Fishman, Jennifer, Sankar, Pamela, Cook-Deegan, Robert, Biesecker, Barbara, Ravitsky, Vardit, Borry, Pascal, K. Cho, Mildred, Ungar, Wendy, J., Ossorio, Pilar, Kato, Kazuto, Wilson, Brenda, McGuire, Amy, Soo-Jin Lee, Sandra, Caulfield, Timothy, Rothenberg, Karen, Rousseau, Francois, Etchegary, Holly, Carroll, June C.
The cost of whole genome sequencing is dropping rapidly. There has been a great deal of enthusiasm about the potential for this technological advance to transform clinical care. Given the interest and significant investment in genomics, this seems an ideal time to consider what the evidence tells...
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2008-01-01
Caulfield, Timothy, McGuire, Amy L., Cho, Mildred, Buchanan, Janet A., Burgess, Michael M., Danilczyk, Ursula, Diaz, Christina M., Fryer-Edwards, Kelly, Green, Shane K., Hodosh, Marc A., Juengst, Eric T., Kaye, Jane, Kedes, Laurence, Knoppers, Bartha M., Lemmens, Trudo, Meslin, Eric M., Murphy, Juli, Nussbaum, Robert L., Otlowski, Margaret, Pullman, Daryl, Ray, Peter N., Sugarman, Jeremy, Timmons, Michael
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2014
Plastow, G., Stothard, P., Moore, S., Bao, H., Meng, Y., Liao, X.
Gene duplication is a widespread phenomenon in genome evolution, and it has been proposed to serve as an engine of evolutionary innovation. In the present study, we performed the first comprehensive analysis of duplicate genes in the bovine genome. A total of 3131 putative duplicated gene pairs...