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Homology modeling of Suv39h1 and discovery of its small molecule inhibitors by virtual screening and their in vitro validation
DownloadFall 2013
Epigenetic modifications are carried out by specific enzymes and are reversible making them a viable and attractive target to design inhibitors to reset the epigenetic regulatory machinery of the cell and restore it to its normal state. Suppressor of variegation 3-9 homolog 1 (Suv39h1) is a...
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