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- 1Asomaning, Justice
- 1Fillmore, Natasha
- 1Hargreaves, Katharine Mary.
- 1McNamara, Allison M
- 1Mita, Raja
- 1Nagendran, Jeevan
- 3Department of Agricultural, Food, and Nutritional Science
- 2Department of Medicine
- 2Department of Oncology
- 2Department of Pharmacology
- 1Department of Food Science
- 1Department of Foods and Nutrition
- 1Ambrose, Divakar (Department of Agricultural, Food and Nutritional Science)
- 1Baker, Kristi (Oncology)
- 1Bressler, David C. (Agricultural, Food and Nutritional Science)
- 1Dyck, Jason RB (Pediatrics)/ McAlister, Finlay A (Medicine)
- 1Foxcroft, George (Department of Agricultural, Food and Nutritional Science)
- 1Godbout, Roseline (Oncology)
Understanding the role of diets enriched in long chain fatty acids on postpartum reproductive function and embryo development in dairy cowsDownload
The objectives of this work were to investigate the influence of diets enriched in long chain fatty acids on feed intake, calf birth weight, maternal and neonatal fatty acid profiles, milk production, postpartum reproductive function, early embryonic development and its transcriptome profile in...
There are increasing social and economic pressures to develop renewable alternatives to fossil derived fuels and chemicals as well as renewable and biodegradable industrial and consumer products and materials. This has led to renewed focus on converting agricultural and forestry feedstocks...
Patients diagnosed with malignant glioma tumours have median survivals of 1.6 yrs and 5 months, respectively, highlighting the deadly nature of this disease. Despite aggressive multimodal treatment, patients with malignant glioma often present with secondary brain tumours at sites distal to the...
All mammalian cells rely on adenosine triphosphate (ATP) to maintain function and for survival. The heart has the highest basal ATP demand of any organ due to the necessity for continuous contraction. As such, the ability of the cardiomyocyte to monitor cellular energy status and adapt the supply...
Litter birth weight phenotype and maternal n-3 long-chain polyunsaturated fatty acid supplementation in pigsDownload
Research reported in this thesis investigated effects of n-3 polyunsaturated fatty acid (LCPUFA) supplementation, litter birth weight phenotype, and their possible interactions, on reproductive performance of the gilt and sow and postnatal performance of the litter. In an initial study, LCPUFA...
Heart failure is associated with major changes in cardiac energy metabolism that decrease cardiac efficiency, which can reduce cardiac function. In severe heart failure there is a shift back toward a fetal heart metabolism, with a decrease in mitochondrial oxidative metabolism and increase in...
Multiple sources suggest that insulin resistance and derangements of cardiac metabolism are among the earliest signs of type-2 diabetes detected in the heart. Unfortunately, limited evidence reflects early changes in cardiac mitochondrial metabolism linked to the development of this disease....