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Spring 2023
The discontinuous split-gene structure is a core feature of eukaryotic gene architecture and requires pre-mRNA splicing to remove silent intron sequences from the initial pre-mRNA transcript before it becomes a mature mRNA suitable for protein synthesis. Splicing begins with recognition of both...
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Understanding the evolution of the membrane trafficking system in diverse eukaryotes through comparative genomics and transcriptomics
DownloadSpring 2018
Single-celled organisms represent the majority of eukaryotic diversity. Recent advances in sequencing technologies have been critical for understanding the evolutionary biology and cell biology of microbial eukaryotes. Comparative genomic analyses have shown that many genes that underlie...