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Skip to Search Results- 1Akhnokh, Maria Kodsy
- 1BATCHU, SRI NAGARJUN
- 1Bai, Helin Daniel
- 1Bosnjak, Natasa
- 1Close, Anne-Françoise J
- 1Davis-Street, Janis.
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Fall 2009
This project investigated the effects of exercise and epinephrine on the mRNA expression of peroxisome proliferator activated receptor gamma coactivator-1 alpha (PGC-1 alpha), a master regulator of mitochondrial biogenesis, in rat adipose tissue. Rats that swam 2 hours daily for 4 weeks had...
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Spring 2016
Mitochondria are at the center of cardiac health and disease. These vital organelles provide most of the energy to the contractile apparatus and play a strategic role in cardiomyocyte survival during cellular stress. Cardiovascular diseases and many aging related diseases are often associated...
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Fall 2023
12,13-dihydroxy-9z-octadecenoic acid (12,13-DiHOME) is a linoleic acid-derived cardiac metabolite produced in endotoxin-induced cardiomyopathy, correlating with myocardial dysfunction, inflammation, and mitochondrial damage. The contribution of 12,13-DiHOME to inflammation in the heart is...
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Fall 2019
Breast cancer is the leading cause of death among women worldwide. Fortunately, death rates have been declining since 1990, due to the increase in early detection, testing, and improved treatment. However, despite the advancement of targeted and hormone therapies for certain molecular sub-types...
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The Cardioprotective Role of the N-3 PUFA Metabolite 19,20-Epoxydocosapentaenoic Acid (19,20-EDP) in the Setting of Ischemia Reperfusion Injury
DownloadSpring 2022
Ischemic heart disease (IHD) is a leading cause of cardiovascular morbidity and mortality worldwide. Myocardial ischemia occurs when a coronary artery is occluded and consequently blood supply to the heart is restricted depleting it of oxygen and nutrients. Although early myocardial reperfusion,...
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Understanding Heart Failure in Patients with Dilated Cardiomyopathy: A Direct Tissue Analysis from Explanted Human Hearts
DownloadFall 2022
Background Chronic heart failure (HF) remains a rising global epidemic that affects both adults and children population. The causes of HF are heterogeneous, and syndromes are often complicated by concomitant disorders such as iron deficiency (ID) and diabetes. Comorbidities not only complicate...