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Skip to Search Results- 1Brophy, Taylor Raymond
- 1Chu, Kevin
- 1Clifford, Alexander M
- 1Collins, Catherine Elizabeth Victoria
- 1Davis-Street, Janis.
- 1Elezzabi, Muhammad A.
- 7Department of Agricultural, Food, and Nutritional Science
- 3Department of Medicine
- 3Department of Pharmacology
- 2Department of Biological Sciences
- 2Faculty of Pharmacy and Pharmaceutical Sciences
- 1Department of Cell Biology
- 1Baker, Glen (Psychiatry)
- 1Carla M. Prado (Agricultural, Food, and Nutritional Science)
- 1Davidge, Sandra T. (Physiology/Obstetrics and Gynecology)
- 1Dr. Andrew Mason (Medicine)
- 1Dr. Dion R. Brocks, Faculty of Pharmacy and Pharmaceutical Sciences
- 1Dyck, Jason RB (Pediatrics)/ McAlister, Finlay A (Medicine)
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Body Composition Assessment in Pediatric Obesity: Reliability, Validity, and Clinical Applications
DownloadFall 2020
Adipose tissue and skeletal muscle have unique metabolic roles. Despite body mass index for age and sex (BMI z-score) being historically widely used to evaluate and monitor health status in children with obesity, it does not depict adiposity and muscularity (or their changes) during growth or...
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Characterization of the Mitochondrial Phenotype Associated with Primary Biliary Cholangitis
DownloadSpring 2017
Primary Biliary Cholangitis (PBC) is a chronic liver disease characterized by the immune-mediated destruction of intra-hepatic bile ducts. The autoimmune nature of PBC involves humoral and cell-mediated responses that target endogenous mitochondrial proteins. It is thought that the breakdown of...
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Chronic Fatigue Mechanisms in Autoimmune Diseases: Lessons from Primary Biliary Cholangitis and Systemic Sclerosis
DownloadFall 2023
Systemic sclerosis (SSc) is an autoimmune disease affecting the body's connective tissues, resulting in progressive fibrosis and vasculopathy. In some cases, individuals with SSc may also develop primary biliary cholangitis (PBC), another autoimmune disease characterized by damage to their...
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Fall 2021
One third of all deaths in Canada are due to cardiovascular diseases, including heart failure. Cardiovascular diseases have a considerable economic burden, and drastically impact the health and quality of life of Canadians. Heart failure (HF) is a clinical condition where the heart is unable to...
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Spring 2021
Lifestyle modifications that induce energy deficit, such as diet and physical activity are considered the cornerstone of weight management. The overall purpose of this research was to compare the effects of an acute nutritional intervention comprised of a high-protein (HP) diet replacement versus...
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Fall 2020
Eukaryotic cells are characterized by the presence of membrane-bound organelles. Close proximity between organelles has been observed for decades, but only recently we have really started to understand the importance of these contacts for cellular function. These contacts consist of areas of...
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Fall 2016
Multiple sources suggest that insulin resistance and derangements of cardiac metabolism are among the earliest signs of type-2 diabetes detected in the heart. Unfortunately, limited evidence reflects early changes in cardiac mitochondrial metabolism linked to the development of this disease....