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A Study of the Protein Phosphatase 1 (PP1) Regulatory Subunit, TIMAP, in Human Glomerular Endothelial Cells
DownloadFall 2015
TIMAP is a prenylated endothelial-predominant regulatory subunit for the serine/threonine (Ser,S/Thr,T) protein phosphatase 1 catalytic subunit (PP1c). TIMAP was first discovered in glomerular endothelial cells. It is expressed in the developing blood vessels of kidney, and its transcription in...
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Spring 2017
Von Willebrand Factor (VWF) is a multimeric adhesive glycoprotein that is exclusively expressed in endothelial cells (EC) and megakaryocytes. This procoagulant protein is involved in maintaining primary hemostasis and thrombus formation. However, there are pathological and physiological...
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Fall 2022
Heart transplantation (HTx) is a life-saving intervention for patients with end-stage heart failure. Nonetheless, the development of Chronic Allograft Vasculopathy (CAV) limits the longevity of transplanted cardiac allografts and the survival of recipients. The pathogenesis of CAV begins with a...