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Spring 2021
A thorough overview of esters and their reductions is presented. A large focus was placed on reductions via homogeneous catalytic hydrogenation. Although several ester hydrogenation systems have been developed, the production of highly enantioenriched alcohols has generally relied upon the usage...
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Design and Development of Chiral Catalysts for Highly Enantioselective Hydrogenation of Amides via Dynamic Kinetic Resolution Under Low Pressure at Room Temperature
DownloadFall 2017
Amide reduction has a long, important history in pharmaceutical and related chemical industries. Traditional stoichiometric reduction methods suffer from numerous drawbacks such as limited functional group tolerance, poor atom economy, and environmental issues. Over the past two decades,...