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Skip to Search Results- 8University of Alberta, Department of Biological Sciences
- 5Wang, J.
- 5Wishart, D.S.
- 4Stothard, Paul
- 4Yu, Jun
- 3Cruz, J.A.
- 32Biological Sciences, Department of
- 26Graduate and Postdoctoral Studies (GPS), Faculty of
- 26Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 24Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 8Biological Sciences, Department of/BioSci OER
- 5Agricultural, Food and Nutritional Science, Department of
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Fall 2017
Merlin and the ezrin-radixin-moesin (ERM) proteins are key organizers of the cell cortex through linking membrane-associated proteins to the underlying actin cytoskeleton. Merlin and the ERM proteins have been implicated in the maintenance of cell integrity, adhesion, and motility during tissue...
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Characterization of the crosstalk between immunity and metabolism in Drosophila melanogaster model
DownloadFall 2021
Immune and metabolic pathways collectively contribute to the containment of microbial invaders, and persistent activation of immune responses contribute to the development of severe metabolic disorders. To determine how interaction between innate immune system and metabolic responses affected...
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CycA is involved in the control of endoreplication dynamics in the Drosophila bristle lineage
Download2012
Campbell, S.D., Sallé, J., Gho, M., Audibert, A.
Endocycles, which are characterised by repeated rounds of DNA replication without intervening mitosis, are involved in developmental processes associated with an increase in metabolic cell activity and are part of terminal differentiation. Endocycles are currently viewed as a restriction of the...
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Cyclic Adenosine Monophosphate (cAMP) and Fragile X Mental Retardation Protein (FMRP) Mediate Avoidance Behaviour in Drosophila
DownloadFall 2016
Fragile X Syndrome (FXS) is neurodevelopmental disorder caused by a trinucleotide CGG repeat expansion that leads to the methylation and transcriptional silencing of the Fragile X mental retardation 1 (fmr1) gene. This results in the loss of Fragile X mental retardation protein (FMRP), an...
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Development of a porcine (Sus scofus) embryo-specific microarray: Annotation and validation
Download2012
Dobrinsky, John, Zhou, Chi, Pasternak, J. Alexander, Dyck, Michael K., Foxcroft, George R., Nieminen, Julie, Tsoi, Stephen, Rigault, Philippe, Sirard, Marc-André, Robert, Claude, Grant, Jason R.
Background The domestic pig is an important livestock species and there is strong interest in the factors that affect the development of viable embryos and offspring in this species. A limited understanding of the molecular mechanisms involved in early embryonic development has inhibited our...
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Divergent genes for translation inition factor elF-4A are coordinately expressed in tobacco
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Kuhlemeir, Cris, Holfmann, Sylvia, Owtrim, George W.
Three cDNA clones coding for eukaryotic translation initiation factor 4A, elF-4A, were isolated from a Nicotiana plumbaginifolia root cDNA library by heterologous screening. The clones comprise two distinct gene classes as two clones are highly similar while the third is divergent. The genes...
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Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins, a major forest pest
Download2013-01-01
Chan, Simon K., Henderson, Hannah, Sperling, Felix A. H., Docking, Roderick T., Palmquist, Diana L., Nguyen, Anh, Zhao, Yongjun, Birol, Inanc, Pandoh, Pawan, Li, Maria, Taylor, Greg A., Liao, Nancy Y., Moore, Richard, Bohlmann, Joerg, Janes, Jasmine K., Jackman, Shaun D., Yuen, Macaire M. S., Huber, Dezene P. W., Jones, Steven J. M., Keeling, Christopher I.
Background The mountain pine beetle, Dendroctonus ponderosae Hopkins, is the most serious insect pest of western North American pine forests. A recent outbreak destroyed more than 15 million hectares of pine forests, with major environmental effects on forest health, and economic effects on the...
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Spring 2015
Cholesterol is well known for its adverse cardiovascular effects, however it has crucial cellular roles. For instance, cholesterol is a key component of eukaryotic cell membranes and constitutes the principle steroid hormone precursor in most animals. Cellular cholesterol concentrations have to...
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Drosophila Mage, a component of Smc5/6 DNA response complex, confers resistance to caffeine and genotoxic stress and plays a role in the cell cycle and cell survival
DownloadFall 2014
Over 50 Melanoma-associated antigen (MAGE) genes have been identified in the human genome. They share a conserved 200 amino acid MAGE-homology domain (MHD). In yeast, the only MAGE homolog (Nse3) is a component of the Smc5/6 DNA damage response complex. In humans, MAGE proteins influence cell...