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Skip to Search Results- 21Graduate and Postdoctoral Studies (GPS), Faculty of
- 21Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 5Biochemistry, Department of
- 5Biochemistry, Department of/Journal Articles (Biochemistry)
- 3Biological Sciences, Department of
- 3Biological Sciences, Department of/Journal Articles (Biological Sciences)
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Spring 2011
Forkhead (Fox) proteins are transcription factors that function in many processes including development, metabolism and cell cycle regulation. This gene family is divided into subfamilies that appear to originate from a common ancestor. I have identified the evolutionary selection pressures...
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Identification of a putative quantitative trait nucleotide in guanylate binding protein 5 for host response to PRRS virus infection
Download2015
Choi, I., Guan, L., Plastow, G. S., Liu, P., Koltes, J. E., Loyd, H., Boddicker, N. J., Eisley, C. J., Schroyen, M., Bao, H., Dekkers, J. C. M., Kommadath, A., Abrams, S. M., Reecy, J. M., Rowland, R. R. R., Serão, N. V. L., Lunney, J. K., Carpenter, S., Stothard, P., Fritz-Waters, E., Tuggle, C. K.
Background Previously, we identified a major quantitative trait locus (QTL) for host response to Porcine Respiratory and Reproductive Syndrome virus (PRRSV) infection in high linkage disequilibrium (LD) with SNP rs80800372 on Sus scrofa chromosome 4 (SSC4). Results Within this QTL,...
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Identification of Hepatotropic Viruses from Plasma Using Deep Sequencing : A Next Generation Diagnostic Tool
Download2013-04-17
Jovel, Juan, Wong, Gane K., Mitchell, Troy , Rahbari, Mandana , Zhang, Yong , Mason, Andrew L., Jordan, Tracy, Law, John , Tian, Zhijian , Song, Deyong , O’keefe, Sandra , Carpenter, Eric, Patterson, Jordan , Wang, Weiwei, Meng, Bo , Wasilenko, Shawn T , Ford, Glenn
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Imag(in)ing the cancerous body: representations of cancer in medical discourse and contemporary visual art
DownloadFall 2010
This thesis examines representations of cancer in contemporary art, with a particular focus on unruly, un-idealized bodies at risk. In bringing together the discourses of art history and medicine, its aim is to engage conventions of visualizing cancer, and more importantly, to highlight the ways...
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Intracellular regulation of matrix metalloproteinase-2 activity: the roles of caveolin-1 and troponin I phosphorylation
DownloadFall 2010
Matrix metalloproteinase‐2 (MMP‐2) was recently revealed to have targets and actions within the cardiac myocyte. In ischemia/reperfusion (I/R) injury, MMP‐2 is activated and degrades troponin I (TnI) and α‐actinin. The regulation of intracellular MMP‐2 activity is relatively unknown and is thus...
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Fall 2019
Cilia are microtubule-based structures that project from nearly every cell in the vertebrate body. While cilia in different contexts can have either sensory or motile functions, all cilia rely upon a core set of genes. When these genes are mutated either singly or in various combinations, a...
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Landscape Ecology of Mule Deer (Odocoileus hemionus) and White-tailed Deer (O. virginianus) with Implications for Chronic Wasting Disease
DownloadFall 2012
Chronic wasting disease (CWD) is a fatal prion disease of cervids that continues to spread into new regions of Canada despite containment efforts. I examine the importance of landscape connectivity using circuit theory and source/sink habitats that are based on selection, survival and...
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Mapping of genomic regions associated with agronomic traits and resistance to diseases in Canadian spring wheat
DownloadSpring 2017
Wheat breeders, in addition to phenotypic selection, employ molecular markers in their programs for different purposes, including parental selection, quality control, analysis of advanced lines (cultivars), on genetic purity and identity, and for markers assisted selection. In the first study of...
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Middle-Aged and Older Adult Walking and Hiking Groups of Cochrane, Alberta: How Outdoor Group Exercise Influences Perceptions of Health, Healing, and Disease
DownloadFall 2011
Middle-aged and older adult walking and hiking groups of Cochrane had unique perceptions of health and healing due to their activities, the equipment they used, the environments they explored, and the relationships they developed. Past anthropological research has focused on aging, ethnomedicine,...
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Mitogen-activated protein kinase-dependent activation of the na+/H+ exchanger is mediated through phosphorylation of amino acids ser(770) and ser(771)
Download2007-01-01
Malo, Mackenzie E., Li, Liang, Fliegel, Larry
We investigated regulation of the type 1 isoform of the Na+/H+ exchanger by phosphorylation. Four specific groups of serine and threonine residues in the regulatory carboxyl-terminal tail were mutated to alanine residues: group 1, S693A; group 2, T718A and S723A/S726A/S729A; group 3,...