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Skip to Search Results- 1Asomaning, Justice
- 1Coleman, Robert J.
- 1Fillmore, Natasha
- 1Hargreaves, Katharine Mary.
- 1McNamara, Allison M
- 1Mita, Raja
- 5Department of Agricultural, Food, and Nutritional Science
- 3Department of Medicine
- 2Department of Oncology
- 2Department of Pharmacology
- 1Department of Food Science
- 1Department of Foods and Nutrition
- 1Ambrose, Divakar (Department of Agricultural, Food and Nutritional Science)
- 1Baker, Kristi (Oncology)
- 1Bressler, David C. (Agricultural, Food and Nutritional Science)
- 1Dr. Andrew Mason (Medicine)
- 1Dyck, Jason RB (Pediatrics)/ McAlister, Finlay A (Medicine)
- 1Evans, David H. (Department of Medical Microbiology and Immunology)
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Characterization of the Mitochondrial Phenotype Associated with Primary Biliary Cholangitis
DownloadSpring 2017
Primary Biliary Cholangitis (PBC) is a chronic liver disease characterized by the immune-mediated destruction of intra-hepatic bile ducts. The autoimmune nature of PBC involves humoral and cell-mediated responses that target endogenous mitochondrial proteins. It is thought that the breakdown of...
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Fall 2016
Multiple sources suggest that insulin resistance and derangements of cardiac metabolism are among the earliest signs of type-2 diabetes detected in the heart. Unfortunately, limited evidence reflects early changes in cardiac mitochondrial metabolism linked to the development of this disease....
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Spring 2016
Heart failure is associated with major changes in cardiac energy metabolism that decrease cardiac efficiency, which can reduce cardiac function. In severe heart failure there is a shift back toward a fetal heart metabolism, with a decrease in mitochondrial oxidative metabolism and increase in...
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Growth of oleaginous yeasts on mixed C5 and C6 sugar streams to generate lipid feedstocks for renewable hydrocarbon production
DownloadSpring 2022
Microbial lipids are a promising feedstock to produce renewable fuels. Lignocellulosic feedstocks can provide multiple carbon sources for microbial growth, such as hexoses (C6) and pentoses (C5). Oleaginous yeasts can convert C5 and C6 sugars to microbial lipids that can be further processed into...
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Spring 2016
Poxviruses, such as vaccinia virus (VACV) and myxoma virus (MYXV), actively modulate various cellular structures and functions to ensure effective replication and transmission. In the contrary, cells use several restriction mechanisms to mitigate these viruses. This evolutionary relationship is...
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Litter birth weight phenotype and maternal n-3 long-chain polyunsaturated fatty acid supplementation in pigs
DownloadSpring 2013
Research reported in this thesis investigated effects of n-3 polyunsaturated fatty acid (LCPUFA) supplementation, litter birth weight phenotype, and their possible interactions, on reproductive performance of the gilt and sow and postnatal performance of the litter. In an initial study, LCPUFA...
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New Insight into the Role of Myocardial Fatty Acid Uptake and Utilization in Health and Disease
DownloadFall 2013
All mammalian cells rely on adenosine triphosphate (ATP) to maintain function and for survival. The heart has the highest basal ATP demand of any organ due to the necessity for continuous contraction. As such, the ability of the cardiomyocyte to monitor cellular energy status and adapt the supply...