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Skip to Search Results- 1Aghamohammadi Sereshki, Arash
- 1Bhardwaj, Paramjit P
- 1Fahreen, Rajani I.
- 1Ferdousi, Mehnaz I
- 1Fung, Terry L
- 1Guo, Huining
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Pre and postnatal maternal distress and infant gut immunity in the Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort
DownloadSpring 2017
Introduction: Secretory immunoglobulin A (sIgA) plays a critical role in gut mucosal immunity and is a marker of immune maturation in early life. Delayed IgA production is associated with increased risk of allergic diseases. Animal models of stressful events before birth and during infancy show...
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Psychosocial Factors Related to Participation and Other Outcomes in Patients with Persistent Back Pain
DownloadSpring 2018
Background: Persistent back pain is a debilitating problem that can threaten many aspects of affected individualsâ lives, including engagement in valued social roles (i.e., participation). Related research often focuses on studying vulnerabilities and deficits, rather than the psychosocial...
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Structural changes of the amygdala subnuclei and limbic white matter tracts in healthy aging and major depressive disorder
DownloadFall 2019
The world population is dramatically aging. Several factors affect brain in healthy aging. The apolipoprotein E (APOE), brain-derived neurotrophic factor (BDNF) and catechol-O-methyl transferase (COMT) might be involved in neurodegenerative diseases, depression and cognitive decline in healthy...
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Structure-Affinity Relationship Study of Novel Imidazoline Ligands at Imidazoline Binding Sites and α-Adrenoceptors
DownloadFall 2014
Many drugs containing an imidazoline moiety are thought to bind to both imidazoline binding sites (IBS) and α-adrenoceptors (α-AR) to mediate their therapeutic effects. To aid in better characterisation of these binding sites, the structure-affinity relationships of several new series of...
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Spring 2024
Mental disorders are one of the leading health problems affecting Canadian children and youth. Teachers are considered frontline workers in child mental health due to the amount of time children spend at school. Given the high prevalence of mental disorders, and the amount of time teachers spend...
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The Development, Feasibility, Acceptability, and Efficacy of a 12-Week Online Mind-Body Intervention for People with Primary Biliary Cholangitis
DownloadFall 2022
Introduction: Persons with primary biliary cholangitis (PBC) experience significantly higher rates of mental distress, impaired health related quality of life (HrQoL), and fatigue than the general population. While mind-body interventions have been shown to improve mental health and HrQoL, and...
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THE PSYCHOSOCIAL FUNCTIONING OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE IN EARLY ADULTHOOD IS IMPAIRED
DownloadFall 2012
Inflammatory bowel disease is a chronic disease that is often diagnosed in childhood and adolescence. The objective of this study was to assess the impact of a diagnosis of IBD on the psychosocial functioning in early adulthood. This was a questionnaire-based cross-sectional study comparing...
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Fall 2011
Worldwide, depression is the leading cause of disability However, its etiology is not yet fully understood. The current research investigated the relationship between early cognitive development and adolescent depression. Two studies were conducted using data from a prospective longitudinal...
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Fall 2016
Depression a disabling chronic illness that crosses borders, cultures, and elements of society. It is well known that there are a number of risk factors for depression including younger age, racial minority status, female sex, presence of substance abuse disorders, chronic illness, and lower...
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The Role of Vitamin D in Anti-Tumor Necrosis Factor-Alpha-Induced Response in Patients with Inflammatory Bowel Disease
DownloadFall 2014
Vitamin D is an important immunomodulator of the immune system and has been suggested to play a role in the pathogenesis of inflammatory bowel disease (IBD). Drugs targeting TNF-alpha are effective IBD therapies, and vitamin D has been demonstrated to suppress TNF-alpha as well as work...