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Subject: Myt1 Departments: Department of Oncology

  • The role of Wee1 and Myt1 in breast cancer

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    Spring 2020

    Lewis, Cody Wayne

    To ensure faithful cell division, entry into mitosis must be inhibited in cells with damage or under-replicated DNA. Wee1 and Myt1 are two partially redundant kinases that inhibit mitotic entry through the phosphorylation of the Cdk1/cyclin B complex. Cdk1 is an essential mitotic kinase that...

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