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Skip to Search Results- 5Chan, Catherine B.
- 5Wheeler, Michael B.
- 4Koshkin, Vasilij
- 3Gänzle, Michael G.
- 2Dyck, Jason R. B.
- 2Gifford, D. J.
- 25Graduate and Postdoctoral Studies (GPS), Faculty of
- 25Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 13Agricultural, Food and Nutritional Science, Department of
- 13Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 2Biological Sciences, Department of
- 2Biological Sciences, Department of/Journal Articles (Biological Sciences)
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The effect of oral lipids and lipoproteins on the biodistribution, metabolism and electrocardiographic side-effects of halofantrine
DownloadSpring 2011
In the past, hyperlipidemia (HL) has been shown to affect the pharmacokinetic and pharmacodynamic properties of lipophilic drugs extensively bound to lipoproteins, including halofantrine (HF). The present thesis examined the effect of HL on the biodistribution, metabolism and electrocardiographic...
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The effects of antidepressants on the phenotype of activated microglia and ischemia-injured cortical neurons
DownloadFall 2013
Depression is one of the most common disorders appearing following a stroke and is also a major factor limiting recovery and rehabilitation in stroke patients. Several antidepressants have shown to have anti-inflammatory properties within the central nervous system (CNS). The major source of...
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The interaction of phenelzine with human monoamine oxidase B: characterization and consequences
DownloadSpring 2022
Phenelzine (PLZ) is a monoamine oxidase (MAO) inhibitor developed in the 1960s which has been used clinically for psychiatric conditions such as depression and anxiety disorders. However, despite over 60 years of research, the mechanism by which PLZ exerts its effects on MAO has yet to be...
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Transport and reaction processes in bioremediation of organic contaminants. 1. Review of bacterial degradation and transport
Download2003-01-01
Bressler, David C., Gray, Murray R.
Bioremediation of contaminants in soil and water involves a complex interplay between transport processes and biological reactions. Equilibrium physical factors such as aqueous solubility, soil adsorption, and phase partitioning indicate the transport processes that can limit bioremediation,...
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Spring 2016
Mild therapeutic hypothermia (HYPO), decreasing brain temperature to 32-35°C, is the gold standard neuroprotectant against ischemia. Cooling also ameliorates several cell death mechanisms in other types of brain injury (e.g., traumatic brain injury). As with many other neuroprotectants, HYPO not...