Search
Skip to Search Results- 3Nykiforuk, Candace I.J.
- 3Olson, J.
- 2Cummings, G. G.
- 2Johnson, Jeffrey A.
- 2McGetrick, Jennifer Ann
- 2Tang, Keren
- 53Graduate and Postdoctoral Studies (GPS), Faculty of
- 53Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 8Nursing, Faculty of
- 5School of Public Health
- 3Nursing, Faculty of/Nursing Education
- 3School of Public Health/Journal Articles (Public Health)
-
The Role of Forkhead Box Transcription Factors in Zebrafish Ocular Development and the Superior Ocular Fissure
DownloadFall 2014
Ocular development is a tightly orchestrated process that is dependent upon precise environmental and genetic factors. Disruption of this can result in microphthalmia, anophthalmia and coloboma (MAC), which is a spectrum of congenital ocular disease with lifelong consequences affecting sight. In...
-
The roles of Pbx and Meis TALE-class homeodomain transcription factors in vertebrate neural patterning
DownloadFall 2010
One of the major goals of developmental biology is to understand how specialized groups of cells arise from an initially unspecified cell population. The vertebrate hindbrain is transiently segmented along its anterior-posterior axis into lineage-restricted compartments called rhombomeres, making...
-
Through the Lens of the Youth: Exploring Culturally Relevant Physical Activity with a Northern Aboriginal Community Through Participatory Action Research
DownloadFall 2014
Guided by an overarching participatory action research framework, this research explored physical activity within the sociocultural context of northern Aboriginal communities. I worked in partnership with the Yellowknives Dene First Nation Community Wellness Program in the Northwest Territories,...
-
Transcriptional regulation of the zebrafish activation-induced cytidine deaminase (AID) gene
DownloadFall 2012
Activation-induced cytidine deaminase (AID, encoded by Aicda) mediates affinity maturation of immunoglobulin genes. Early studies in mammals indicated that the transcription of Aicda was regulated by a number of transcriptional regulatory regions, including a B-cell specific enhancer in the...
-
Transcriptomic analysis of zebrafish prion protein mutants supports conserved cross-species function of the cellular prion protein; and zebrafish as a model for cisplatin induced ototoxicity and transition metals as potential ligands for Tlr4ba and Tlr4bb
DownloadFall 2021
The work presented in this thesis is split between two projects. The first utilises prp1 and prp2 knockout zebrafish to investigate physiological functions of the cellular prion protein (PrPC). The second builds upon the use of zebrafish as a model for hearing loss to confirm a role of toll-like...
-
Translating Knowledge: Promoting Health through Intergenerational Community Arts Programming
Download2016
Fast, Janet, Eales, Jacquie, Anderson, Sharon, Barnet, David, Chivers, Sally, Keating, Norah
Introduction. Intergenerational programs have been touted to address the generation gaps and isolation of older adults. Mutual contact alone has produced mixed results, but attention to the intergenerational program content demonstrates well-being benefits. This practice-based article examines...
-
Understanding Policy-Influencer Perspectives on the Adoption and Spread of Provincial Daily Physical Activity Policies across Canada: A Multiple Case Study
DownloadSpring 2017
Physical activity is an important part of a healthy lifestyle and contributes to improved physical and mental health. In Canada, children are becoming more inactive and are at risk of poor health outcomes and chronic disease. School physical activity policies represent one intervention strategy...
-
Using Local and Traditional Knowledge to Define a Digital Library for the Inuvialuit Settlement Region
Download2016-09-01
Stobbs, R. , Campbell, Sandy, Farnel, S. , Piltingsrud, A. , Shiri, A. , Rathi, D. , Maloney, E. , Cockney, C.
The Digital Library North (DLN) project is a research and development collaboration between the Inuvialuit Cultural Resource Centre (ICRC) located in Inuvik, in Canada’s Northwest Territories and the University of Alberta School of Library and Information Studies in Edmonton, Alberta. The...
-
Using a Zebrafish Animal Model to Identify the First Candidate Gene for Pigmentary Glaucoma
DownloadSpring 2019
Premelanosome protein (PMEL) was identified as a candidate gene for the development of pigment dispersion syndrome (PDS) and pigmentary glaucoma (PG) in humans. Mutations in PMEL were shown to cause pigment and ocular defects in several animals but there is currently no known PMEL associated...