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Skip to Search Results- 22Biological Sciences, Department of
- 22Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 4Agricultural, Food and Nutritional Science, Department of
- 4Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 2Biochemistry, Department of
- 2Biochemistry, Department of/Journal Articles (Biochemistry)
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1995
Abstract: A cluster of genes of the CYP6 family was found in a series of overlapping lambda DASH clones from a genomic library of the house fly, Musca domestica, Four complete genes, CYP6A3, CYP6A4, CYP6A5, and CYP6C1, and fragments of two other genes, CYP6A6 and CYP6C2, were closely linked on a...
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2011
Willing, Benjamin P., Finlay, B. Brett , Thanachayanont, Teerawat, Croxen, Matthew, Vacharaksa, Anjalee
Host resistance to bacterial infections is thought to be dictated by host genetic factors. Infections by the natural murine enteric pathogen Citrobacter rodentium (used as a model of human enteropathogenic and enterohaemorrhagic E. coli infections) vary between mice strains, from mild...
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Amino acid polymorphisms in strictly conserved domains of a P-type ATPase HMA5 are involved in the mechanism of copper tolerance variation in Arabidopsis
Download2008
Kimura, K., Southron-Francis, J. L., Iuchi, S., Furuzawa, A., Taylor, G. J., Kobayashi, Y., Koyama, H., Kobayashi, M., Kuroda, K.
Copper (Cu) is an essential element in plant nutrition, but it inhibits the growth of roots at low concentrations. Accessions of Arabidopsis ( Arabidopsis thaliana) vary in their tolerance to Cu. To understand the molecular mechanism of Cu tolerance in Arabidopsis, we performed quantitative trait...
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Amplified mitochondrial DNA as a diagnostic marker for species of conifer-feeding Choristoneura (Lepidoptera: Tortricidae)
Download1995
Hickey, D. A., Sperling, F. A. H.
Abstract: We describe a method for identifying conifer-feeding species and lineages of Choristoneura Lederer in Canada and Alaska. The method relies on amplification of mitochondrial (mt) DNA by the polymerase chain reaction (PCR); amplified DNA is then digested with restriction enzymes to give...
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An alternative physiological role for the EmhABC efflux pump in Pseudomonas fluorescens cLP6a
Download2011
Background Efflux pumps belonging to the resistance-nodulation-division (RND) superfamily in bacteria are involved in antibiotic resistance and solvent tolerance but have an unknown physiological role. EmhABC, a RND-type efflux pump in Pseudomonas fluorescens strain cLP6a, extrudes hydrophobic...
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2002-01-01
Li, Xiuju J., Alvarez, Bernando, Casey, Joseph R., Reithmeier, Reinhart A. F., Fliegel, Larry
We examined the ability of carbonic anhydrase II to bind to and affect the transport efficiency of the NHE1 isoform of the mammalian Na+/H+ exchanger. The C-terminal region of NHE1 was expressed in Escherichia coli fused with an N-terminal glutathionineS-transferase or with a C-terminal...
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2009
Grant, Jason, Stothard, Paul, Moore, Stephen S., Guan, Leluo, Jin, Weiwu
Background MicroRNAs (miRNAs) are a family of ~22 nucleotide small RNA molecules which regulate gene expression by fully or partially binding to their complementary sequences in mRNAs or promoters. A large number of miRNAs and their expression patterns have been reported in human, mouse and rat....
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Common Low-Density Lipoprotein Receptor p.G116S Variant Has a Large Effect on Plasma Low-Density Lipoprotein Cholesterol in Circumpolar Inuit Populations
Download2014-11-20
Dubé, Joseph B., Wang, Jian, Cao, Henian, McIntyre, Adam D., Johansen, Christopher T., Hopkins, Scarlett E., Stringer, Randa, Hosseinzadeh, Siyavash, Kennedy, Brooke A., Ban, Matthew R., Young, T. Kue, Connelly, Philip W., Dewailly, Eric, Bjerregaard, Peter, Boyer, Bert B., Hegele, Robert A.
"Background: Inuit are considered to be vulnerable to cardiovascular disease because their lifestyles are becoming more Westernized. During sequence analysis of Inuit individuals at extremes of lipid traits, we identified 2 nonsynonymous variants in low-density lipoprotein receptor (LDLR), namely...
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Computational identification of residues that modulate voltage sensitivity of voltage-gated potassium channels
Download2005
Background: Studies of the structure-function relationship in proteins for which no 3D structure is available are often based on inspection of multiple sequence alignments. Many functionally important residues of proteins can be identified because they are conserved during evolution. However,...