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Skip to Search Results- 2Cholangiocarcinoma
- 1Apoptosis
- 1Hepatocellular carcinoma
- 1MitoChip
- 1Mitochondrial dysfunction
- 1MtDNA
- 1Bamforth, Fiona (Co-supervisor, Department of Laboratory Medicine & Pathology)
- 1Bamforth, Fiona (Department of Laboratory Medicine and Pathology)
- 1Sergi, Consolato (Department of Laboratory Medicine and Pathology and Department of Pediatrics)
- 1Sergi, Consolato (Supervisor, Department of Laboratory Medicine & Pathology)
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Mitochondrial Dysfunction and Induction of Apoptosis in Hepatocellular Carcinoma and Cholangiocarcinoma Cell Lines by Thymoquinone
DownloadSpring 2015
Thymoquinone, the plant-based bioactive constituent derived from the volatile oil of Nigella sativa, has been shown to possess considerable anti-neoplastic activity. The present study aimed to investigate the anti-tumour property of TQ against hepatocellular carcinoma (HepG2) and...
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Spring 2013
Cholangiocellular carcinoma (CCA) is the second most common hepatic malignancy, but its carcinogenesis is poorly understood. Somatic mitochondrial DNA (mtDNA) mutations have been demonstrated in a variety of human cancers. However, no study has previously investigated mitochondria and their...