Search
Skip to Search Results- 18Oil Sands Research and Information Network (OSRIN)
- 17Graduate and Postdoctoral Studies (GPS), Faculty of
- 17Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 9Oil Sands Research and Information Network (OSRIN)/AOSERP Reports
- 5Biological Sciences, Department of
- 5Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 3Department of Biochemistry
- 3Faculty of Nursing
- 2Department of Agricultural, Food, and Nutritional Science
- 2Department of Civil and Environmental Engineering
- 2Faculty of Pharmacy and Pharmaceutical Sciences
- 1Department of Agricultural, Food and Nutritional Science
- 1Baracos, Vickie (Oncology, Agricultural, Food, and Nutritional Science)
- 1Brindley, David N. (University of Alberta, Biochemistry)
- 1Dr Vera Mazurak, Agricultural, Food and Nutritional Science
- 1Dr. Afsaneh Lavasanifar (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Dr. Andrew Belch (Department of Oncology, Faculty of Medicine and Dentistry)
- 1Dr. Karin Olson (Faculty of Nursing)
-
Spring 2016
Tamoxifen is the accepted therapy for patients with estrogen receptor α (ERα)−positive breast cancer. However, clinical resistance to tamoxifen, as demonstrated by recurrence or progression on therapy, is frequent and precedes death from metastases. To improve breast cancer treatment it is vital...
-
Toxicity of saline groundwater from Syncrude's Lease 17 to fish and benthic macroinvertebrates
Download1977
Peltzner, A., McMahon, B., McCart, P., Walder, G.
The mining of the tar sands which are included in the area to be developed by Syncrude Canada Ltd. will require the dewatering of the mine pits. This will involve the pumping of large volumes of saline groundwater. Present plans call for its eventual disposal through Ruth Lake, the Poplar River...
-
The role of intestinal microbiota in development of irinotecan toxicity and in toxicity reduction through dietary fibres in rats
Download2014
Baracos, Vickie, Dieleman, Levinus, Farhangfar, Arazm, Lin, Xiaoxi B., Gänzle, Michael G., Sawyer, Michael B., Valcheva, Rosica, Schieber, Andreas
CPT-11 is a drug used as chemotherapy for colorectal cancer. CPT-11 causes toxic side-effects in patients. CPT-11 toxicity has been attributed to the activity of intestinal microbiota, however, intestinal microbiota may also have protective effects in CP!-11 chemotherapy. This study aimed to...
-
1979
Anderson, P. D., D'Apollinia, S., Perry, S., Dick, J., Deluca, J., Spear, P.
This study was initiated in early 1976 during the early stages of the Alberta Oil Sands Environmental Research Program. The goal of the project was the establishment of criteria safeguarding fish from toxic effects of mixtures of vanadium, nickel, and phenol to fish. All three constituents are...
-
1977
The impact of saline waters upon freshwater biota, having special reference to the AOSERP study area, is reviewed. Available information on water quality in the AOSERP study area indicates that: the natural regional surface water quality does not appear to have any toxic effects, and chloride...
-
The evaluation of toxic effects induced by exposure of mammals to oil sands process-affected water and its organic fraction
DownloadSpring 2018
Oil sands process-affected water (OSPW) produced by the surface-mining oil sands industry in Alberta, has been shown to be toxic to a variety of organisms. Much of this toxicity has been attributed to the dissolved organic compounds, primarily naphthenic acids (NAs). Under a no-release practice,...
-
1979
Giles, M. A., Lawrence, S. G., Klaverkamp, J. F.
In order to conduct oil sands mining operations in the surface mining region of the Athabasca oil sands deposits, most regions require depressurization of the basal sandstone formations. The groundwater produced by depressurization operations is of poor enough quality to be toxic to fish. The...
-
Fall 2019
Breast cancer is the leading cause of death among women worldwide. Fortunately, death rates have been declining since 1990, due to the increase in early detection, testing, and improved treatment. However, despite the advancement of targeted and hormone therapies for certain molecular sub-types...
-
2014-09-24
Belosevic, M., Singh, A., Gamal El-Din, M., Li, C., McPhedran, K., Chelme-Ayala, P., Klamerth, N.
Large volumes of oil sands process-affected water (OSPW) are produced by the surface-mining oil sands industry in Alberta. The industry is following a no-release practice for OSPW due to its potential environmental toxicity. Both laboratory and field studies have demonstrated that OSPW is toxic...
-
Quantitative Label-Free Comparative Proteomic Analyses of Eukaryotic Tissues via Mass Spectrometry
DownloadFall 2018
In recent years, rapid advances in genomic and transcriptomic sequencing technologies have enabled the compilation of vast libraries of protein sequences and thus an explosion in bioinformatics-based fields of research. Among these is proteomics – the study of global protein abundance within a...