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Fall 2015
Organic chemistry has its foundations in the 19th century; since, it has grown into a number of industries affecting our daily lives such as the manufacture of goods and life saving pharmaceuticals. The need for new and increasingly efficient synthetic methods has grown in response to the...
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Spring 2012
Fabrication of nanofeatures with precisely defined size and ordering is essential for a broad range of technologically important applications, including integrated circuit production. Self-organizing block copolymers are capable of patterning substrates with nanoscale precision. This thesis...
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Studying Protein–Glycolipid Interactions and Membrane Peptides and Proteins using Electrospray Ionization Mass Spectrometry and Model Membranes
DownloadFall 2018
Membrane systems, including glycolipids (GLs) and membrane peptides and proteins (MPs), play an important role in many cellular processes, such as singling, cellular recognition, transportation, and energy conversion. However, the amphipathic nature of GLs and MPs makes their analysis...
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Synthesis and Application of Colloidal Substrates for In-Solution Surface Enhanced Raman Scattering
DownloadFall 2020
Surface-enhanced Raman scattering (SERS) has evolved into a powerful analytical measurement technique with the potential for single molecule detection. The technological advancement of handheld Raman instrumentation is powering the development of SERS applications in a variety of industries....
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Spring 2012
Germanium nanomaterials have many potential applications based on their size-tunable optical and electronic properties, for example in photodetectors, photovoltaics and non-volatile memory. In this work, the synthesis of Ge nanoparticles by two different methods based on tailorability through the...
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Fall 2020
The synthesis of germanium nanomaterials with well-defined surface chemistry is of considerable interest, not only because of general scientific curiosity but also because of their vast potential applications in optoelectronics, energy storage, and the semiconductor industry. Covalently bonded...
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Synthesis of fragments of a polysaccharide from Nocardia nova for structural and biological studies
DownloadSpring 2020
Nocardia are gram-positive bacteria. Nocardia nova is one of the Nocardia species and can cause serious disease, particularly in immunocompromised patients. Rapid diagnosis of N. nova can be lifesaving. The cell wall of N. nova contains an unusual glucose-modified arabinogalactan polysaccharide...
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Synthetic Main Group and Transition Metal Targets for Electronic and Photovoltaic Applications
DownloadFall 2012
The work presented herein is focused on the synthesis and characterization of inorganic materials for potential use in electronic and photovoltaic applications. Platinum containing complexes of the form LxPt(SC4H2Br)2 (x = 1, L = dppe, dppp; x = 2, L = PBu3, PAr3), were synthesized using...
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The Design, Synthesis and Evaluation of Multivalent Heterobifunctional Ligands Specific for Shiga Toxin 1 and Shiga Toxin 2
DownloadSpring 2014
Hemolytic uremic syndrome (HUS) is a potential life-threatening condition caused by infection with Shiga toxin-producing Escherichia coli O157:H7. There are two major types of Shiga toxins, namely, Shiga toxin 1 (Stx1) and Shiga toxin 2 (Stx2), of which, Stx2 is clinically most closely associated...
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Spring 2022
Iron-sulfur clusters are recognized widely as ancient cofactors that are proposed to have impacted the prebiotic chemistry that led to life. Previous work done by our lab has shown that iron-sulfur clusters could be synthesized prebiotically on cysteine containing tripeptides, but it remains...