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Fall 2017

Bahry, Ashley MA.

Background Intrauterine growth restriction (IUGR) as a result of suboptimal in utero environments can cause perinatal brain injury and ultimately lead to neurodevelopmental disorders (NDD). In the developed world placental insufficiency (PI) is the leading cause of IUGR. This antepartum insult...

Fall 2015

Corrigan, Jennifer

Introduction Cerebral Palsy (CP) is a ubiquitous term used to describe a group of permanent, non-progressive disorders of movement, posture, and behaviour. Despite countless advances in neonatal medicine, the incidence of CP has remained constant in term infants over the last three decades. More...

Fall 2015

Mager, Brianna J

Introduction. Cerebral palsy (CP) is the most frequently occurring cause of movement disorders in children. It has a prevalence of 2-2.5 cases per 1000 live births and is a chronic condition, requiring lifelong rehabilitation. The ability to communicate is a primary factor in positive...

Spring 2018

Smith, Allison T

This thesis discusses the organization of motor pathways in adults and children with cerebral palsy (CP). Individuals with CP experience impairments in the control of head and neck functions. The cranial nerves that innervate the head and neck pass through the brainstem. Thus, motor impairment...

Fall 2017

Langlois, Colette M.

Producing speech that is clear, audible, and intelligible to others is a challenge for many children with cerebral palsy (CP) and children with Down syndrome (DS). Previous studies have demonstrated the effectiveness of using the Lee Silverman Voice Treatment (LSVT LOUD®) to increase vocal...

Fall 2021

Fleming, Cassidy Ley

BackgroundChildhood apraxia of speech (CAS) has attracted controversy in the field of speech-language pathology for decades. There is some agreement that CAS is a neurological speech sound disorder that impairs a child’s ability to plan and/or program the precise and sequential movements required...

Fall 2016

Przyslupski, Ann-Marie T

Hypoxic-ischemic brain damage (HIBD) is still of major concern in the neonatal period, resulting in chronic neurological sequelae stemming from damage to the term newborn brain. Full-body and focal-head cooling within 6 hours of birth have proven neuroprotective in human newborns and various...

Fall 2016

Nguyen, Antoinette

Introduction Maternal infection and inflammation leading to a fetal inflammatory response (FIR) is a risk factor for perinatal brain damage. Perinatal brain injury can lead to neurodevelopmental disorders, the sine quo non outcome parameter of which is cerebral palsy (CP). Despite advances in...

Spring 2018

Najafi, Mohammad

Physical interaction with the environment and object manipulation play an important role in the development of children's cognitive and perceptual skills. For children who have severe physical impairments, one of the biggest concerns is the loss of opportunities for play. Robots can be used to...

Fall 2016

Condliffe, Elizabeth, G

This thesis discusses the pathophysiological mechanisms underlying neuromotor impairments in people with spastic cerebral palsy (CP). Ninety percent of people with CP have spastic CP and 60% have bilateral motor impairments. The first two chapters introduce CP and review the mechanisms known to...