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Spring 2014
The TOB (Topogenesis of Outer membrane β-barrel proteins) complex is composed of the core proteins Tob55 (Sam50), Tob37 (Sam37) and Tob38 (Sam35). The complex facilitates the insertion of all β-barrel and some α-helically anchored integral proteins into the mitochondrial outer membrane (MOM)....
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Investigation of transcriptional and translational regulation of the Neurospora crassa alternative oxidase
DownloadFall 2018
Mitochondria are organelles found in most eukaryotes and supply the cell with the majority of its energy needs in the form of ATP. Most of the proteins needed for mitochondrial function are nuclear encoded. Therefore, mitochondria communicate their functional status to the nucleus, resulting in...
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The role of the ERMES complex in the assembly of mitochondrial outer membrane proteins in the filamentous fungus Neurospora crassa
DownloadFall 2012
The ERMES (endoplasmic reticulum-mitochondria encounter structure) is composed of the Mdm10, Mdm12, Mmm1 and Mmm2 proteins, and acts as a tether between mitochondria and the endoplasmic reticulum (ER). Mutations affecting any of the proteins in the structure are associated with a variety of...