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Skip to Search Results- 1Asomaning, Justice
- 1Fillmore, Natasha
- 1Hargreaves, Katharine Mary.
- 1Hartt, Donald J.
- 1McNamara, Allison M
- 1Mita, Raja
- 4Department of Agricultural, Food, and Nutritional Science
- 3Department of Medicine
- 3Department of Pharmacology
- 2Department of Oncology
- 1Department of Food Science
- 1Department of Foods and Nutrition
- 1Ambrose, Divakar (Department of Agricultural, Food and Nutritional Science)
- 1Baker, Kristi (Oncology)
- 1Bressler, David C. (Agricultural, Food and Nutritional Science)
- 1Dr. Andrew Mason (Medicine)
- 1Dyck, Jason RB (Pediatrics)/ McAlister, Finlay A (Medicine)
- 1Evans, David H. (Department of Medical Microbiology and Immunology)
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Regulation of Anti-tumor Immunity in Colorectal Cancer by Interaction of Exosome Immune Complexes with Fc gamma Receptors
DownloadSpring 2019
Targeted therapy is difficult for colorectal cancer (CRC) due to lack of conserved tumor associated antigens (TAA). Immunotherapies for CRC directed at TAA that can overcome intestinal tolerance need to be developed to improve survival of CRC patients. Exosomes are extracellular vesicles secreted...
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Characterization of the Mitochondrial Phenotype Associated with Primary Biliary Cholangitis
DownloadSpring 2017
Primary Biliary Cholangitis (PBC) is a chronic liver disease characterized by the immune-mediated destruction of intra-hepatic bile ducts. The autoimmune nature of PBC involves humoral and cell-mediated responses that target endogenous mitochondrial proteins. It is thought that the breakdown of...
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Fall 2016
Multiple sources suggest that insulin resistance and derangements of cardiac metabolism are among the earliest signs of type-2 diabetes detected in the heart. Unfortunately, limited evidence reflects early changes in cardiac mitochondrial metabolism linked to the development of this disease....
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Spring 2016
Heart failure is associated with major changes in cardiac energy metabolism that decrease cardiac efficiency, which can reduce cardiac function. In severe heart failure there is a shift back toward a fetal heart metabolism, with a decrease in mitochondrial oxidative metabolism and increase in...
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Growth of oleaginous yeasts on mixed C5 and C6 sugar streams to generate lipid feedstocks for renewable hydrocarbon production
DownloadSpring 2022
Microbial lipids are a promising feedstock to produce renewable fuels. Lignocellulosic feedstocks can provide multiple carbon sources for microbial growth, such as hexoses (C6) and pentoses (C5). Oleaginous yeasts can convert C5 and C6 sugars to microbial lipids that can be further processed into...
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Spring 2016
Poxviruses, such as vaccinia virus (VACV) and myxoma virus (MYXV), actively modulate various cellular structures and functions to ensure effective replication and transmission. In the contrary, cells use several restriction mechanisms to mitigate these viruses. This evolutionary relationship is...