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Skip to Search Results- 1Asomaning, Justice
- 1Buijs, David, M
- 1Cheng Baron, June
- 1Fillmore, Natasha
- 1Halpin, Anne M
- 1Hargreaves, Katharine Mary.
- 5Department of Agricultural, Food, and Nutritional Science
- 3Department of Pharmacology
- 2Department of Medicine
- 2Department of Oncology
- 2Department of Physiology
- 1Department of Food Science
- 1Ambrose, Divakar (Department of Agricultural, Food and Nutritional Science)
- 1Baker, Kristi (Oncology)
- 1Bressler, David C. (Agricultural, Food and Nutritional Science)
- 1Davidge, Sandra T. (Physiology/Obstetrics and Gynecology)
- 1Dyck, Jason RB (Pediatrics)/ McAlister, Finlay A (Medicine)
- 1Febbraio,Maria (Dentistry)
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Litter birth weight phenotype and maternal n-3 long-chain polyunsaturated fatty acid supplementation in pigs
DownloadSpring 2013
Research reported in this thesis investigated effects of n-3 polyunsaturated fatty acid (LCPUFA) supplementation, litter birth weight phenotype, and their possible interactions, on reproductive performance of the gilt and sow and postnatal performance of the litter. In an initial study, LCPUFA...
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Long-term cardiovascular and metabolic effects of hypoxia-induced intrauterine growth restriction
DownloadSpring 2011
Rueda-Clausen, Christian Federico
Cardiovascular and metabolic diseases are still the primary cause of death and disability in modern society. Although genetic factors play a fundamental role in the development of these chronic conditions, the remarkable variability in an individual’s susceptibility to develop these pathologies...
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New Insight into the Role of Myocardial Fatty Acid Uptake and Utilization in Health and Disease
DownloadFall 2013
All mammalian cells rely on adenosine triphosphate (ATP) to maintain function and for survival. The heart has the highest basal ATP demand of any organ due to the necessity for continuous contraction. As such, the ability of the cardiomyocyte to monitor cellular energy status and adapt the supply...
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Spring 2013
Diastolic dysfunction is the primary cause of 40–50% of all heart failure cases and is a contributing factor in many cardiac conditions, resulting from delayed or slowed muscle relaxation, increased stiffness of the relaxed heart or from poor systolic function which reduces the elastic recoil of...
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Regulation of Anti-tumor Immunity in Colorectal Cancer by Interaction of Exosome Immune Complexes with Fc gamma Receptors
DownloadSpring 2019
Targeted therapy is difficult for colorectal cancer (CRC) due to lack of conserved tumor associated antigens (TAA). Immunotherapies for CRC directed at TAA that can overcome intestinal tolerance need to be developed to improve survival of CRC patients. Exosomes are extracellular vesicles secreted...
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Fall 2010
Patients diagnosed with malignant glioma tumours have median survivals of 1.6 yrs and 5 months, respectively, highlighting the deadly nature of this disease. Despite aggressive multimodal treatment, patients with malignant glioma often present with secondary brain tumours at sites distal to the...
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Spring 2024
Background and Objective High-fat Western diets have been linked to the dysregulation of fatty acids (FA) and glucose intake in tissues, resulting in adverse metabolic outcomes such as obesity, insulin resistance, and atherosclerosis. There is a pressing need for new therapeutic approaches to...
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Spring 2013
Background: Exercise adherence is particularly low among elderly patients with low functional capacity. Purpose: This study was undertaken to assess the relationship between measures of physical function (PF) with physical activity (PA) in elderly cardiac patients. Methods: PF was assessed in...