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Skip to Search Results- 1Abdrabou, Abdalla
- 1Abdul Rahman, Siti Aishah
- 1Abu-Sa'da, Omar SD
- 1Alles, Sascha R
- 1Aulakh, Amit
- 1Baedke, Jessica
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Manipulation of Seed Carbon Flow from Cellulose to Lipid and Protein Biosynthesis in Arabidopsis to Accelerate the Characterization of Protein-Related Genes in Canola
DownloadFall 2023
Canola (Brassica napus L.) is the major oilseed crop in Canada. After oil extraction, the protein-rich seed meal (around 40% protein) serves as a nutritious feedstock for animals and the protein fraction has potential for human consumption. However, excess fiber in the seed meal (about 33%) can...
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Fall 2009
The computational ability of principal neurons and interneurons in the brain and their ability to work together in concert are thought to underlie higher order cognitive processes such as learning, memory, and attention. Dendrites play a very important role in neuronal information processing...
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Modulation of Spontaneous Neural Network Bursting in Newborn Rat Brain Slices by Extracellular Calcium, Methylxanthines, and Opioids
DownloadFall 2012
Spontaneous neuronal bursting appears to be pivotal for brain maturation. This thesis studied such synchronized neural network oscillations in immature newborn rat hippocampus, cortex, and locus coeruleus. For this, horizontal brain slices were generated for (simultaneous) suction electrode...
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Pharmacological and Fluorometric Assessment of Neuronal KCNQ Channels, and Implications for Understanding Neurological Disease
DownloadSpring 2020
Epilepsy affects 60 million people worldwide, and encompasses the most common forms of neurological disorders. Epilepsy manifests in diverse ways in patients, ranging from mild cognitive effects, to seizures, to the more severe epileptic encephalopathy. While many pharmacological approaches exist...
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Fall 2013
Glomus cells of the carotid body are peripheral chemoreceptors that detect changes in arterial oxygen levels. Hypoxia suppresses oxygen-sensitive K+ channels in glomus cells, resulting in cytosolic Ca2+ ([Ca2+]i) elevation in glomus cells via the activation of voltage-gated Ca2+ channels. The...
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Regulation of Cardiac Gap Junctional Communication: Metabolic regulation of Cx40 and Cx43 via phosphorylation
DownloadFall 2015
Alterations in myocardial metabolism and cardiac electrophysiology associated with structural heart disease generate lethal arrhythmias. Differential levels of energy (ATP) supply and demand are generated with structural heart disease that is expected to activate 5’-amp activated protein kinase...
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Fall 2023
Sleep is a vital neurobiological process, yet despite its fundamental significance, delineating the endogenous neural pathways involved has been slow to progress due to a lack of diverse sleep models. Anesthesia, which has direct behavioural parallels to natural sleep, and which is often linked...
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Spring 2011
Large corporations have a significant amount of working capital tied into the acquisition and storage of spare parts. In the industry, spare parts inventory policies and strategies are often developed in isolation from reliability centered maintenance practices – this results in significant...
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The Effect of Caffeine on the Neurobehavioral and Neuropathological Outcome of the Newborn Rat
DownloadSpring 2010
Caffeine is used for the treatment of apnea of prematurity. The objective of this study was to determine the long term neuropathological and neurobehavioral effects of caffeine on the immature rat brain. Newborn rats were injected with either caffeine, or normal saline from postnatal days 3 to 7,...