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- 2Caenorhabditis-elegans embryos
- 2Mitotic spindle
- 1C-elegans
- 1Centriolar
- 1Cytoplasmic dynein
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2012
Müller-Reichert, T., Greenan, G., O'Toole, E., Srayko, M., Lange, K.I.
As part of a multi-subunit ring complex, γ-tubulin has been shown to promote microtubule nucleation both in vitro and in vivo, and the structural properties of the complex suggest that it also seals the minus ends of the polymers with a conical cap. Cells depleted of γ-tubulin, however, still...
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Visualization of dynein-dependent microtubule gliding at the cell cortex: implications for spindle positioning
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Dynein motors move along the microtubule (MT) lattice in a processive “walking” manner. In the one-cell Caenorhabditis elegans embryo, dynein is required for spindle-pulling forces during mitosis. Posteriorly directed spindle-pulling forces are higher than anteriorly directed forces, and this...
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