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Skip to Search Results- 3Protein engineering
- 2Biosensors
- 2Fluorescent proteins
- 1FRET
- 1Fluorescence imaging
- 1Fluorescent protein
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Fall 2016
Fluorescence microscopy is currently the most powerful imaging technique for interrogation of neural circuits. Accordingly, tremendous efforts have been invested in engineering fluorescent proteins (FPs) to act as indicators for various biochemical processes in neural circuits, resulting in a...
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Fall 2013
The discovery of green fluorescent protein (GFP) from the Aequorea victoria Jellyfish followed by the extensive efforts of protein engineers to produce other fluorescent proteins (FPs) spanning the visible color spectrum made fluorescent proteins indispensable biochemical tools in the scientific...
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Spring 2017
Fluorescent proteins (FPs) have dramatically advanced life science research. Since their discovery they have become invaluable tools for imaging living systems and have been developed into precision instruments for measuring normally invisible events such as fluctuations in calcium ion...
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Spring 2015
Fluorescent proteins (FP) and FP-based biosensors have become essential tools for cell biology and neuroscience research. This thesis describes efforts to engineer new FPs with red emission and novel genetically encoded biosensors based on red FPs. Directed evolution and semi-rational design are...