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Skip to Search Results- 12Agricultural, Food and Nutritional Science, Department of
- 12Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 7Biological Sciences, Department of
- 7Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 5Renewable Resources, Department of
- 5Renewable Resources, Department of/Journal Articles (Renewable Resources)
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Glucose-regulated glucagon secretion requires insulin receptor expression in pancreatic α-cells
Download2005
Chan, Catherine B., Wheeler, Michael B., Asghar, Zeenat, Diao, Jingyu
The insulin receptor (IR) and its signaling appear to be essential for insulin secretion from pancreatic β-cells. However, much less is known about the role of the IR in α-cells. To assess the role of the IR in glucagon and insulin secretion, we engineered adeno-viruses for high efficiency small...
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High levels of green-tree retention are required to preserve ground beetle biodiversity in boreal mixedwood forests
Download2010
Jacobs, J.J., Volney, W.J.A., Work, T.T., Spence, J.R.
Recovery of biodiversity and other ecosystem functions to pre-disturbance levels is a central goal of natural disturbance-based approaches to ecosystem management. In boreal mixedwood forests, green-tree retention has been proposed as an alternative approach to traditional clearcutting that may...
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Impaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesity
Download2010
Kuo, Ming-Shang, Dyck, Jason R. B., Sletten, Torunn, Proctor, Spencer D., Jacobs, René L., Lingrell, Susanne, Cao, Guoqing, Peake, David A., Kennedy, Brian P., Zhao, Yang, Vance, Dennis E., Koonen, Debby P. Y., Su, Brian
Phosphatidylcholine (PC) is synthesized from choline via the CDP-choline pathway. Liver cells can also synthesize PC via the sequential methylation of phosphatidylethanolamine, catalyzed by phosphatidylethanolamine N-methyltransferase (PEMT). The current study investigates whether or not hepatic...
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Increased rate of fatty acid uptake and plasmalemmal fatty acid transporters in obese Zucker rats
Download2001
Arumugam, Yoga, Luiken, Joost J. F. P., Dyck, David J., Bonen, Arend, Tandon, Narendra N., Pelsers, Maurice M. L., Bell, Rhonda C., Turcotte, Lorraine P., Glatz, Jan F. C.
Giant vesicles were used to study the rates of uptake of long-chain fatty acids by heart, skeletal muscle, and adipose tissue of obese and lean Zucker rats. With obesity there was an increase in vesicular fatty acid uptake of 1.8-fold in heart, muscle and adipose tissue. In some tissues only...
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Limited impacts of extensive human land use on dominance, specialization, and biotic homogenization in boreal plant communities
Download2015-01-01
Mayor, S. J., Boutin, S., He, F., Cahill, J. F.
Background Niche theory predicts that human disturbance should influence the assembly of communities, favouring functionally homogeneous communities dominated by few but widespread generalists. The decline and loss of specialists leaves communities with species that are functionally more similar....
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Limited mitochondrial permeabilization is an early manifestation of palmitate-induced lipotoxicity in pancreatic ß-cells
Download2008
Wheeler, Michael B., Chan, Catherine B., Dai, Feihan F., Koshkin, Vasilij, Robson-Doucette, Christine A.
Involvement of the mitochondrial permeability transition (MPT) pore in early stages of lipotoxic stress in the pancreatic β-cell lines MIN6 and INS-1 was the focus of this study. Both long term (indirect) and acute (direct) effects of fatty acid (FA) application on β-cell susceptibility to...
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2012
Follador, Rainer, Gänzle, Michael G.
Oligosaccharides, compounds that are composed of 2–10 monosaccharide residues, are major carbohydrate sources in habitats populated by lactobacilli. Moreover, oligosaccharide metabolism is essential for ecological fitness of lactobacilli. Disaccharide metabolism by lactobacilli is well...
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2000
Abbont, S. P., Lumley, T. C., Currah, R. S.
Abstract: During a survey of microfungi from rotting wood in northern Alberta forests, 49 species of ascomycetes, representing 24 genera, and 15 families in seven orders, were recovered. Twenty-eight species are new reports for Alberta, 15 of which are new for Canada, and seven are new for North...
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2003
Chan, Catherine B., Wang, Xiaolin, Koshkin, Vasilij, Wheeler, Michael B., Scherer, Philipp E.
Excessive free fatty acid (FFA) exposure represents a potentially important diabetogenic condition that can impair insulin secretion from pancreatic β-cells. Because mitochondrial oxidative phosphorylation is a main link between glucose metabolism and insulin secretion, in the present work we...
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2015-01-01
Donovan, S.K., Jones, B., Harper, D.A.T.
The first fossil echinoids are recorded from the Cayman Islands. A regular echinoid, Arbacia? sp., the spatangoids Brissus sp. cf. B. oblongus Wright and Schizaster sp. cf. S. americanus (Clark), and the clypeasteroid Clypeaster sp. are from the Middle Miocene Cayman Formation. Test fragments of...