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Skip to Search Results- 2Zhao, Richard
- 1Adamson, J.
- 1Alabi, Adekunle
- 1Alrabeeah, Abdollah A. M.
- 1Andermatt, Matthias
- 1Bangma, J.
- 38Graduate and Postdoctoral Studies (GPS), Faculty of
- 38Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 2Agricultural, Food and Nutritional Science, Department of
- 2Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 2Communications and Technology Graduate Program
- 2Communications and Technology Graduate Program/Capping Projects (Communications and Technology)
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Glial Expression of Amyloid Precursor Protein (APP) and its Processing Enzymes in the ANPC Mouse Model
DownloadFall 2021
Alzheimer’s disease (AD) is a complex and progressive neurodegenerative disorder believed to be triggered by the accumulation of β-amyloid (Aβ) peptides derived from the proteolytic processing of amyloid precursor protein (APP). The regions primarily affected in AD brains are the hippocampus and...
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Identifying seasonal Lake Sturgeon (Acipenser fulvescens) movement patterns and habitat selection in the South Saskatchewan River Basin
DownloadFall 2016
Lake Sturgeon (Acipenser fulvescens Rafinesque 1817) have experienced population declines throughout their range. In Alberta, low density age-class distributions, irregular recruitment, critically low spawning potential ratios and other factors led to a 2007 designation of “Threatened” for this...
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Influence of lipids (arachidonic acid and cholesterol) on calcium signalling in rodent pancreatic beta cells
DownloadFall 2010
Ca2+ is an important mediator of stimulus-secretion coupling in beta cells of the pancreatic islets, which secrete insulin in response to elevation in plasma glucose concentration. I studied the actions of two lipids, arachidonic acid (AA) and cholesterol, on enzymatically-dissociated single...
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Insights into Membrane Type-1 Matrix Metalloproteinase cleavage of the Low-density Lipoprotein Receptor
DownloadSpring 2021
The Low-density lipoprotein receptor (LDLR) mediated cellular uptake of LDL is the main pathway for plasma LDL cholesterol (LDL-C) clearance. However, the LDLR can be proteolytically cleaved to release its soluble ectodomain (sLDLR) into the extracellular milieu and as such reducing its LDL-C...
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Investigating the Role of PCSK9 C-terminal Domain in the Regulation of Low-Density Lipoprotein Receptor and Cholesterol Metabolism
DownloadSpring 2020
Atherosclerotic cardiovascular disease (CVD) is the leading cause of death worldwide. Long-term elevated low-density lipoprotein cholesterol (LDL-C) levels are the major risk factors for the development of atherosclerotic lesions, which can eventually lead to myocardial infarction and many...
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2015-10-14
SSHRC Awarded IG 2016: Project aims to catalogue, edit and analyze Early Modern Icelandic religious poetry whose subjects are virgin martyr saints. The project seeks to demonstrate the critical role of the poems within Early Modern Icelandic religious and social thought as prescriptive models for...
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Fall 2010
Because of their high strength to weight ratio, stiffened steel plates are often used in light structures where plates are placed into compression. The stability of steel plates stiffened with longitudinal tee-shaped stiffeners and subjected to uniaxial compression or combined axial compression...
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Fall 2017
The nucleus is a hallmark of eukaryotic cells. It segregates the genetic material from the cytoplasm. The nucleus is encapsulated by the nuclear envelope which is perforated with nuclear pore complexes (NPCs), macromolecular structures formed by proteins termed nucleoporins (Nups). NPCs and...
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Relationships among diverse root foraging behaviours: understanding plant behavioural types
DownloadSpring 2014
Behaviours capture the functional response of plants to environmental factors. I explore behaviours for twenty co-occurring grassland species in response to common belowground environmental factors (competition, mycorrhizae, heterogeneous and high nutrients) and their relationship to plant...