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- 2Reactive oxygen species
- 1Anti-cancer
- 1Bioenergetics
- 1Complex II
- 1D112
- 1Delocalized lipophilic cation
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Deciphering the mechanism of cytotoxicity and cancer-selective activity of the delocalized lipophilic cation D112
DownloadFall 2016
Chemotherapeutic drugs that are used in anti-cancer treatments often cause death of both cancerous and noncancerous cells. This non-selective toxicity is the root cause of untoward side effects that limits the effectiveness of therapy. To improve the therapeutic options for cancer patients, there...
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Fall 2011
Complex II, or succinate dehydrogenase, is a vital component of aerobic life. Its function is critical for both the tricarboxylic acid cycle and the mitochondrial respiratory chain since it catalyzes the oxidation of succinate to fumarate, liberating two electrons that feed into the lipid-soluble...
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