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Skip to Search Results- 2Bacterial Toxins
- 1Antibodies
- 1Food Safety
- 1High Hydrostatic Pressure
- 1Mass Spectrometry (MS)
- 1Protein-Protein Interactions
- 1Ehrmann, Matthias A.
- 1Eugenio, Luiz
- 1Gänzle, Michael G.
- 1Hussack, Greg
- 1Kitova, Elena N.
- 1Klassen, John S.
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2005
Vogel, Rudi F., Märtlbauer, Erwin, Ehrmann, Matthias A., Gänzle, Michael G., Margosch, Dirk, Moravek, Maximilian
Even though the inactivation of microorganisms by high pressure treatment is a subject of intense investigations, the effect of high pressure on bacterial toxins has not been studied so far. In this study, the influence of combined pressure/temperature treatment (0.1 to 800 MPa and 5 to 121 °C)...
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Structural basis for antibody recognition in the receptor-binding domains of toxins A and B from Clostridium difficile
Download2014
Ng, Kenneth K. S., Tanha, Jamshid, Kitova, Elena N., Eugenio, Luiz, Murase, Tomohiko, Klassen, John S., Hussack, Greg, Schorr, Melissa
Clostridium difficile infection is a serious and highly prevalent nosocomial disease in which the two large, Rho-glucosylating toxins TcdA and TcdB are the main virulence factors. We report for the first time crystal structures revealing how neutralizing and non-neutralizing single-domain...