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Skip to Search Results- 1Adisakwattana, Sirichai
- 1Beilin, Lawrence J.
- 1Betti, Mirko
- 1Blackmore, Derrick
- 1Branion, Richard M.R.
- 1Chan, Catherine B.
- 14Graduate and Postdoctoral Studies (GPS), Faculty of
- 14Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 4Agricultural, Food and Nutritional Science, Department of
- 4Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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- 2Sustainable Forest Management Network/Project Reports (Sustainable Forest Management Network)
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Beyond the Antibodies: Sera Metabolomic Biomarker Signatures Discriminate Myasthenic And Healthy Cohorts
DownloadFall 2018
Myasthenia Gravis (MG) is a chronic, potentially debilitating autoimmune disease characterized by weakness and rapid fatigue of the voluntary muscles that worsens on exertion and improves on rest. Left untreated, MG symptoms may cause significant morbidity, affecting occupational performance,...
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Chronic Fatigue Mechanisms in Autoimmune Diseases: Lessons from Primary Biliary Cholangitis and Systemic Sclerosis
DownloadFall 2023
Systemic sclerosis (SSc) is an autoimmune disease affecting the body's connective tissues, resulting in progressive fibrosis and vasculopathy. In some cases, individuals with SSc may also develop primary biliary cholangitis (PBC), another autoimmune disease characterized by damage to their...
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Contributions of Bim and Nur77 to multiple mechanisms of T cell tolerance following high affinity antigen encounter
DownloadSpring 2015
Prevention of autoimmune disease requires the elimination or inactivation of T cells that are highly reactive to self-peptides. During T cell development in the thymus, self-reactive thymocytes undergo negative selection upon receiving a high affinity T cell receptor (TCR) signal following...
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Conversion of cycloalk-2-enones into 2-methylcycloalkane-1,3-diones - Assessment of various Tamao-Fleming procedures and mechanistic insight into the use of the Me3SiMe2Si unit.
Download2016-01-01
Yu, Goujun, Clive, Derrick L. J.
Conjugate addition of Me3SiMe2SiLi to cycloalk-2-en-1-ones, ketalization, Tamao-Fleming oxidation (Bu4NF, then H2O2, KHCO3), TPAP oxidation and acid hydrolysis generates 2-methyl cycloalkane-1,3-diones. Ketalization is needed in order to prevent addition of Me3Si- to the carbonyl. The...
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Dietary oxysterols are incorporated in plasma triglyceride rich lipoproteins, increase their susceptibility to oxidation and increase aortic cholesterol concentration of rabbits
Download1998
Mamo, John C. L., Croft, Kevin D., Vine, Donna F., Mori, Tetsuya, Beilin, Lawrence J.
Early fatty streaks and advanced lesions are characterized by the deposition of cholesterol and cholesterol oxidation products (oxysterols). Oxysterols have been shown to be cytotoxic and pro-atherogenic compared to cholesterol and are found in cholesterol-rich processed foods. The consumption of...
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First-Row Transition Metal-Mediated Reactions: Catalytic Ester Hydrogenolysis, Aerobic Alkane Oxidation, and [5+2] Ring-Expansion Reactions
DownloadSpring 2014
The research described in this dissertation focuses on first-row transition metal catalyzed and mediated organic reactions. The first part of the thesis involves the exploration of the catalytic reactivity of phosphoranimide-supported tetrametallic nickel and cobalt clusters, while the second...
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Inactivation of Salmonella spp. in wheat flour by 395 nm pulsed light emitting diode (LED) treatment and the related functional and structural changes of gluten
Download2020-01-01
Du, Lihui, Prasad, Amritha Jaya, Gänzle, Michael G., Roopesh, M.S.
Salmonella spp. is one of the top foodborne pathogens associated with low-moisture foods and they exhibit significant resistance to conventional thermal treatments. UV light pulses emitted from light emitting diode (LED) has shown antimicrobial potential in high-moisture foods and water. However,...