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Skip to Search Results- 9Arachidonic acid
- 4Electrophysiology
- 4Neuropathic pain
- 3Cardiac hypertrophy
- 3Docosahexaenoic acid
- 2Cytochrome P450
- 1Afhami, Shima
- 1Aghazadeh Habashi, Ali
- 1Al Lawati, Hanan M
- 1Alles, Sascha R
- 1Alsaad,Abdulaziz M
- 1Beaulieu, Michael J.
- 1Brocks, Dion (Pharmacy and Pharmaceutical Sciences)
- 1Dr. Ayman El-Kadi
- 1El-Kadi, Ayman (Faculty of pharmacy and pharmaceutical sciences)
- 1El-Kadi, Ayman (Pharmacy and Pharmaceutical Sciences)
- 1Field, Catherine (Agricultural, Food and Nutritional Science)
- 1Field, Catherine J. (Agriculture, Food and Nutritional Science)
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Profiling the Bacterial and Fungal Gut Microbiome of Children with and without Prader-Willi Syndrome (PWS)
DownloadFall 2020
Obesity is a complex multifactorial disease that has a large array of direct (e.g. altered metabolic and inflammatory profile) and indirect (e.g. mental health concerns etc.) consequences on health and is associated with increased morbidity and mortality. Prader-Willi Syndrome (PWS) is the most...
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Role of CYP-mediated Arachidonic Acid Metabolites in Development of Cardiac Hypertrophy and Chronic Doxorubicin-induced Cardiotoxicity
DownloadSpring 2013
Drug-induced cardiotoxicity is classified as a predisposing factor leading to cardiac hypertrophy and heart failure. Of importance, doxorubicin (DOX, adriamycin) is considered as an effective anticancer agent whose major limiting side effect is cardiotoxicity. Of importance, several studies...
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Fall 2019
Persistent hyperexcitability in the primary sensory afferents contributes substantially to the onset and the maintenance of neuropathic pain. Inteleukin-1β (IL-1β) has been implicated to directly interact with interleukin 1 receptor type I (IL-1RI) expressed in dorsal root ganglion (DRG) neurons...
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The effect of long-term interleukin-1 beta exposure on sensory neuron electrical membrane properties: implications for neuropathic pain
DownloadSpring 2011
The effect of interleukin-1 beta (IL-1β) on the electrical properties of sensory neurons was assessed at comparable levels and exposure times to those found in animal models of neuropathic pain. Experiments involved whole cell current- or voltage-clamp recordings from rat dorsal root ganglion...
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The role of cytochrome P450 derived arachidonic acid metabolites against Angiotensin II-induced cardiac hypertrophy in Sprague Dawley rats and the RL-14 cell line
DownloadFall 2015
Several cytochrome P450 (CYP) enzymes and their arachidonic acid (AA) metabolites play essential roles in the maintenance of cardiovascular health, and their alteration gives rise to a number of cardiovascular diseases, including cardiac hypertrophy and heart failure. Recent data demonstrated...