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Skip to Search Results- 1Aghazadeh Habashi, Ali
- 1Al Lawati, Hanan M
- 1Alsaad,Abdulaziz M
- 1Anderson, Warren G.
- 1Asomaning, Justice
- 1Beaulieu, Michael J.
- 8Department of Agricultural, Food, and Nutritional Science
- 5Faculty of Pharmacy and Pharmaceutical Sciences
- 3Department of Oncology
- 2Department of Medicine
- 2Department of Pharmacology
- 1Centre for Neuroscience
- 1Ambrose, Divakar (Department of Agricultural, Food and Nutritional Science)
- 1Baker, Kristi (Oncology)
- 1Bressler, David C. (Agricultural, Food and Nutritional Science)
- 1Brocks, Dion (Pharmacy and Pharmaceutical Sciences)
- 1Dr. Ayman El-Kadi
- 1Dyck, Jason RB (Pediatrics)/ McAlister, Finlay A (Medicine)
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Role of CYP-mediated Arachidonic Acid Metabolites in Development of Cardiac Hypertrophy and Chronic Doxorubicin-induced Cardiotoxicity
DownloadSpring 2013
Drug-induced cardiotoxicity is classified as a predisposing factor leading to cardiac hypertrophy and heart failure. Of importance, doxorubicin (DOX, adriamycin) is considered as an effective anticancer agent whose major limiting side effect is cardiotoxicity. Of importance, several studies...
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Spring 2024
Background and Objective High-fat Western diets have been linked to the dysregulation of fatty acids (FA) and glucose intake in tissues, resulting in adverse metabolic outcomes such as obesity, insulin resistance, and atherosclerosis. There is a pressing need for new therapeutic approaches to...
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The role of cytochrome P450 derived arachidonic acid metabolites against Angiotensin II-induced cardiac hypertrophy in Sprague Dawley rats and the RL-14 cell line
DownloadFall 2015
Several cytochrome P450 (CYP) enzymes and their arachidonic acid (AA) metabolites play essential roles in the maintenance of cardiovascular health, and their alteration gives rise to a number of cardiovascular diseases, including cardiac hypertrophy and heart failure. Recent data demonstrated...
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Spring 2014
There are increasing social and economic pressures to develop renewable alternatives to fossil derived fuels and chemicals as well as renewable and biodegradable industrial and consumer products and materials. This has led to renewed focus on converting agricultural and forestry feedstocks...
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Understanding the role of diets enriched in long chain fatty acids on postpartum reproductive function and embryo development in dairy cows
DownloadSpring 2016
The objectives of this work were to investigate the influence of diets enriched in long chain fatty acids on feed intake, calf birth weight, maternal and neonatal fatty acid profiles, milk production, postpartum reproductive function, early embryonic development and its transcriptome profile in...