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2015-02-05

Berry, Tanya R

Survey data collected for the CIHR funded study \"Pink Ribbons and Red Dresses: the relationship between disease awareness campaigns, health-related cognitions and perceptions of preventive behaviours.\"

Spring 2024

Douglas, Claire

Breast cancer is the second most common cancer in Canada. It is estimated that one in eight Canadian women will be diagnosed with the disease in their lifetime. Neoadjuvant chemotherapy is often prescribed to improve surgical resection outcomes and reduce micrometastases. Achieving a pathological...

Fall 2018

Kramer, David A

In recent years, rapid advances in genomic and transcriptomic sequencing technologies have enabled the compilation of vast libraries of protein sequences and thus an explosion in bioinformatics-based fields of research. Among these is proteomics – the study of global protein abundance within a...

1995

Leithoff, Jacqueline M.

Fall 2017

Close, Anne-Françoise J

Background: The insulin-secreting pancreatic beta-cell plays a central role in the maintenance of glucose homeostasis and in the pathogenesis of both type 1 and type 2 diabetes mellitus. In both cases, production of pro-inflammatory cytokines causes beta-cell apoptosis, which results in the...

Fall 2009

Mok, Sue-Ann

The survival of several neuron populations during development, including sympathetic neurons, is strictly regulated by neurotrophins such as nerve growth factor (NGF) released from innervation targets. NGF activates its receptor, TrkA, at axon terminals, to generate signals that are transmitted...

Spring 2016

Perreault, Amanda C

There is currently no clinically approved, widely used molecular imaging agent for in vivo detection of cell death. Such an agent would be highly useful for early assessment of treatment efficacy in cancer patients, as well as for monitoring many other diseases in which cell death plays an...

Fall 2019

Mann, Jasdeep

Breast cancer is the leading cause of death among women worldwide. Fortunately, death rates have been declining since 1990, due to the increase in early detection, testing, and improved treatment. However, despite the advancement of targeted and hormone therapies for certain molecular sub-types...

Spring 2017

Mehta, Ninad

Apoptosis serves as a powerful defense against damaged and unwanted cells. The family of Bcl-2 proteins plays a key role in the regulation of apoptosis at the mitochondria. Members of the Bcl-2 family include pro- and anti-apoptotic members that collectively determine the state of the cell....

Fall 2014

Stach, Tara R

Ocular development is a tightly orchestrated process that is dependent upon precise environmental and genetic factors. Disruption of this can result in microphthalmia, anophthalmia and coloboma (MAC), which is a spectrum of congenital ocular disease with lifelong consequences affecting sight. In...