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The contribution of Sting and Nlrp3 activation to anti-tumour immunity in microsatellite instable colorectal cancer
DownloadFall 2019
The constant exposure of the intestine to antigens forces the mucosal immune system to be tolerant to avoid a constitutively inflamed state. Unfortunately, immune tolerance can allow colorectal cancers (CRCs) to escape detection. The majority of CRCs are chromosomally instable (CIN) and display...
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