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Skip to Search Results- 1Briney, Bryan
- 1Burton, Dennis R.
- 1Cottrell, Christoph A.
- 1Eugenio, Luiz
- 1Hsueh, Jessica
- 1Hussack, Greg
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Holes in the glycan shield of the native HIV envelope are a target of trimer-elicited neutralizing antibodies
Download2016
Hsueh, Jessica, Menis, Sergey, Sanders, Rogier W., Ozorowski, Gabriel, Pauthner, Matthias, Voss, James E., van Gils, Marit J., Torres, Jonathan L., McCoy, Laura E., Ward, Andrew B., Wilson, Ian A., Schief, William R., Macauley, Matthew S., Burton, Dennis R., Cottrell, Christoph A., Messmer, Terrence, Sok, Devin, Briney, Bryan, Kulp, Daniel W.
A major advance in the search for an HIV vaccine has been the development of a near-native Envelope trimer (BG505 SOSIP.664) that can induce robust autologous Tier 2 neutralization. Here, potently neutralizing monoclonal antibodies (nAbs) from rabbits immunized with BG505 SOSIP.664 are shown to...
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Structural basis for antibody recognition in the receptor-binding domains of toxins A and B from Clostridium difficile
Download2014
Ng, Kenneth K. S., Tanha, Jamshid, Kitova, Elena N., Eugenio, Luiz, Murase, Tomohiko, Klassen, John S., Hussack, Greg, Schorr, Melissa
Clostridium difficile infection is a serious and highly prevalent nosocomial disease in which the two large, Rho-glucosylating toxins TcdA and TcdB are the main virulence factors. We report for the first time crystal structures revealing how neutralizing and non-neutralizing single-domain...