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Skip to Search Results- 1Athanassakis-Vassiliadis, Irene
- 1Boadu, Nana Yaa Agyeman
- 1Brooks, Hannah M
- 1Charchuk, Rhianna M
- 1Chou, Ying
- 1Davey, Ashley
- 3Department of Medical Microbiology and Immunology
- 3School of Public Health
- 2Department of Agricultural, Food, and Nutritional Science
- 2Department of Medical Sciences
- 1Department of Chemistry
- 1Department of Immunology
- 1Ambrose, Divakar (Department of Agricultural, Food and Nutritional Science)
- 1Bell, Rhonda (Department of Agricultural, Food, and Nutritional Science)
- 1Davidge, Sandra T (Obstetrics and Gynecology/ Physiology)
- 1Derda, Ratmir (Department of Chemistry)
- 1Guilbert, Larry J (Medical Microbiology and Immunology
- 1Hawkes, Michael (Pediatrics)
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Anti-Malarial Strategies Among Vulnerable Populations: exploring bed net underutilization among internally displaced persons and novel adjunctive therapies for cerebral malaria
DownloadFall 2017
Background: Despite declining incidence globally, malaria morbidity and mortality remain elevated among internally displaced persons (IDPs) and children under five, particularly in sub-Saharan Africa. Malaria prevention and treatment efforts in the Democratic Republic of the Congo (DRC) are...
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Clinical impact of submicroscopic malaria on delivery outcomes and the role of VAR2CSA antibodies in pregnant women from Colombia
DownloadFall 2018
Malaria caused by the genus Plasmodium (P.) is one of the oldest and most important parasitic infections globally. Pregnant women are at an increased risk for malaria, where the disease poses a significant risk to both maternal and child health. Better diagnosis of malaria can have an immediate...
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High fructose intake during pregnancy adversely affects insulin resistance, lipid profiles, and affects placental gene expression of nutrient transporters and angiogenesis in rat dams and their pregnant offspring
DownloadSpring 2017
Fructose intake has increased over the past several decades due to high consumption of sugary foods and drinks. In non-pregnant humans and animals, high fructose intake results in hyperlipidemia, insulin resistance and weight gain, although its effects on metabolic adaptations to pregnancy and on...
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Investigation of antibody-mediated immune mechanisms during submicroscopic infections of pregnancy-associated malaria in pregnant women from Colombia
DownloadFall 2021
Malaria has been a threat to humans for centuries and continues to be a global health problem. Repeated exposure to malaria in childhood can result in protective immunity that reduces parasite invasion of red blood cells and the sequestration of infected red blood cells (iRBC) in the tissues....
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Investigation of the immunological cross-reactivity between Plasmodium vivax Duffy Binding Protein and Plasmodium falciparum VAR2CSA for vaccine development
DownloadFall 2021
Worldwide, an estimated 30 million pregnancies are at risk of malaria infection each year. In pregnancy, Plasmodium falciparum parasites express a protein called VAR2CSA that mediates adherence of infected red blood cells (iRBCs) to chondroitin sulfate A (CSA) in the placenta. VAR2CSA antibodies...
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Investigation of the Molecular Mechanisms That Determine Isolate-Specific, Antibody-Mediated Neutralization of HCV infectivity
DownloadFall 2018
It is estimated that there are about 1.75 million new Hepatitis C Virus (HCV) infections per year worldwide and around 20% will develop liver cirrhosis or liver cancer if left untreated. Direct acting antiviral drugs are available for the treatment of HCV with success rates of over 90%. But...
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Fall 2013
The placenta is an essential transitory fetal organ responsible for the key processes of nutrient, oxygen, and waste transfer between the mother and the fetus throughout gestation. Placental size is, importantly, known to correlate to fetal weight, and the malfunction and malformation of the...
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Phage Display Derived Fragment-based Discovery of Antigens for Antibodies associated with Mycobacterial Infections
DownloadSpring 2017
Tuberculosis (TB) remains a global health problem. Incorrect or missed serodiagnosis for TB, especially in resource-limited settings, is one of the main reasons for TB epidemics. Clinically, serological tests that use circulating antibodies are attractive because antibodies in serum are present...