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Skip to Search Results- 2Fliegel, Larry
- 2Michalak, M.
- 1Abdul Rahman, Siti Aishah
- 1Alles, Sascha R
- 1Arantes, A. S.
- 1Asher, B.J.
- 19Graduate and Postdoctoral Studies (GPS), Faculty of
- 19Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 4Agricultural, Food and Nutritional Science, Department of
- 4Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 3Biological Sciences, Department of
- 3Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 5Centre for Neuroscience
- 3Department of Pharmacology
- 3Department of Physiology
- 3Neuroscience
- 1Department of Biological Sciences
- 1Department of Chemical and Materials Engineering
- 2Tse, Amy (Centre for Neuroscience and Department of Pharmacology)
- 1Ballanyi, Klaus (Physiology Department, University of Alberta)
- 1Chen, Xing-Zhen (Physiology)
- 1Clayton T. Dickson (Psychology, Physiology, Anesthesia and Pain Medicine, Neuroscience and Mental Health Institute)
- 1Colmers, William F. (Pharmacology)
- 1Dickson, Clayton (Neuroscience and Mental Health Institute, Psychology, Physiology, Anesthesiology and Pain Medicine
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Fall 2013
Glomus cells of the carotid body are peripheral chemoreceptors that detect changes in arterial oxygen levels. Hypoxia suppresses oxygen-sensitive K+ channels in glomus cells, resulting in cytosolic Ca2+ ([Ca2+]i) elevation in glomus cells via the activation of voltage-gated Ca2+ channels. The...
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Regulation of Cardiac Gap Junctional Communication: Metabolic regulation of Cx40 and Cx43 via phosphorylation
DownloadFall 2015
Alterations in myocardial metabolism and cardiac electrophysiology associated with structural heart disease generate lethal arrhythmias. Differential levels of energy (ATP) supply and demand are generated with structural heart disease that is expected to activate 5’-amp activated protein kinase...
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2005
van Houten, B., Patel, M., Chan, C. B., Orrenius, S. , Fariss, M. W.
Oxidative stress and mitochondrial oxidative damage have been implicated in the etiology of numerous common diseases. The critical mitochondrial events responsible for oxidative stress–mediated cell death (toxic oxidative stress), however, have yet to be defined. Several oxidative events...
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Fall 2023
Sleep is a vital neurobiological process, yet despite its fundamental significance, delineating the endogenous neural pathways involved has been slow to progress due to a lack of diverse sleep models. Anesthesia, which has direct behavioural parallels to natural sleep, and which is often linked...
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The effect of long-term interleukin-1 beta exposure on sensory neuron electrical membrane properties: implications for neuropathic pain
DownloadSpring 2011
The effect of interleukin-1 beta (IL-1β) on the electrical properties of sensory neurons was assessed at comparable levels and exposure times to those found in animal models of neuropathic pain. Experiments involved whole cell current- or voltage-clamp recordings from rat dorsal root ganglion...
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Fall 2015
Nucleosides are essential for RNA and DNA synthesis. They also play a central role in other cellular metabolic pathways, and modulate a diverse array of physiological processes, including renal and cardiovascular function and neurotransmission. Due to their hydrophilic nature, specialized...
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Transcriptome profiling of the small intestinal epithelium in germfree versus conventional piglets
Download2007
Beever, Jonathan E., Band, Mark R., Marini, Juan C., Schook, Lawrence B., Chowdhury, Shankar R., Rund, Laurie A., Willing, Benjamin P., Gaskins, H. Rex, King, Dale E., Loor, Juan J., Lane, Adrienne B., Van Kessel, Andrew G.
Background To gain insight into host-microbe interactions in a piglet model, a functional genomics approach was used to address the working hypothesis that transcriptionally regulated genes associated with promoting epithelial barrier function are activated as a defensive response to the...
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2018-01-15
Khan, Amanda S., Chu, Jackson W. F., Leys, Sally P.
Sponges link the microbial loop with benthic communities by feeding on bacteria. Glass sponge reefs on the continental shelf of western Canada have extremely high grazing rates, consuming seven times more particulate carbon than can be supplied by vertical flux alone. Unlike many sponges, the...