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Skip to Search Results- 1Athanassakis-Vassiliadis, Irene
- 1Berke, Sheldon S
- 1Chahal, Manik
- 1Davey, Ashley
- 1Diakur, James Michael.
- 1Eu, Soon Ming.
- 3Department of Agricultural, Food, and Nutritional Science
- 3Department of Medicine
- 3Department of Oncology
- 2Department of Laboratory Medicine and Pathology
- 2Department of Medical Sciences
- 2Faculty of Pharmacy and Pharmaceutical Sciences
- 1Abdulkarim, Bassam (Oncology)
- 1Allan Murray (Medicine)
- 1Ambrose, Divakar (Department of Agricultural, Food and Nutritional Science)
- 1Bell, Rhonda (Department of Agricultural, Food, and Nutritional Science)
- 1Davidge, Sandra T (Obstetrics and Gynecology/ Physiology)
- 1Dr. Ralf Schirrmacher (Oncology)
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Manipulation of the Angiogenic Balance by Pharmacological Inhibition of Platelet PKC Signalling
DownloadFall 2012
Blood platelets mediate wound healing by preventing bleeding and by supporting growth of new blood vessels. Blood vessel growth is supported in part by growth factors released from platelet α-granules. Both platelet aggregation and α-granule release are mediated by intracellular signaling...
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Fall 2013
The placenta is an essential transitory fetal organ responsible for the key processes of nutrient, oxygen, and waste transfer between the mother and the fetus throughout gestation. Placental size is, importantly, known to correlate to fetal weight, and the malfunction and malformation of the...
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Novel Insights into the Role of O6-Methylguanine-DNA Methyltransferase in Glioblastoma Angiogenesis, Invasion, and Proliferation
DownloadFall 2012
Glioblastoma multiforme (GBM) is characterized by aberrant angiogenesis, rapid proliferation, and widespread invasion through the brain parenchyma. Thus, the prognosis for these tumors remains extremely poor despite aggressive multimodal treatment including chemotherapy with the alkylating agent...
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Plasma Membrane Organization and Endocytosis of CD36 in Human Microvascular Endothelial Cells
DownloadSpring 2016
The plasma membrane is a dynamic lipid bilayer that surrounds the cell, embedded with different plasma membrane proteins, aiding communication between the inside and outside of the cells. Its functions are achieved through an intricate organization of lipid-lipid, lipid-protein and...
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Spring 2011
Human Cytomegalovirus (HCMV) is the most common cause of congenital infection in newborns. One mechanism for this virus to reach the fetus is to cross the placenta through the syncytiotrophoblast layer. Accumulation and protection of pathogens in the syncytiotrophoblast could affect the systemic...
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Fall 2013
Thrombotic microangiopathies are group of diseases that refer to clinical and pathological syndromes where endothelial injury results in the manifestations of capillary thrombosis, microangiopathic hemolytic anemia, schistocytosis, and can lead to renal failure. In this thesis we aimed to study...