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Skip to Search Results- 37Graduate and Postdoctoral Studies (GPS), Faculty of
- 37Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 16Biological Sciences, Department of
- 16Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 7Chemistry, Department of
- 7Chemistry, Department of/Journal Articles (Chemistry)
- 12Department of Chemistry
- 4Department of Agricultural, Food, and Nutritional Science
- 4Department of Electrical and Computer Engineering
- 3Faculty of Pharmacy and Pharmaceutical Sciences
- 2Department of Biochemistry
- 2Department of Chemical and Materials Engineering
- 4Vederas, John (Chemistry)
- 2Kurgan, Lukasz (Electrical and Computer Engineering)
- 2Unsworth, Larry (Chemical and Materials Engineering)
- 1Ball, Ronald O. (Department of Agricultural, Food and Nutritional Science)
- 1Ballermann, Barbara (Medicine)
- 1Boekhoven, Job (Chemistry, Technical University of Munich)
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Ectopic expression of human and feline CD9 in a Human B cell line confers ß1 integrin-dependent motility on fibronectin and laminin substrates and enhanced tyrosine phosphorylation
Download1995-01-01
Shaw, Andrew R. E., Domanska, Agatha, Mak, Allan, Gilchrist, Anita, Dobler, Kelly, Visser, Lydia, Poppema, Sibrand, Fliegel, Larry, Letarte, Michelle, Willett, Brian J.
Few molecules have been shown to confer cell motility. Although the motility-arresting properties of anti-CD9 monoclonal antibody (mAb) suggest the transmembrane 4 superfamily (TM4SF) member CD9 can induce a motorgenic signal, gene transfection studies have failed to confirm this hypothesis. We...
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Spring 2013
Moraes, Thania Gislaine Vasconcelos de
The effects of broiler breeder dietary energy and protein during rearing and dietary energy level of lay diets on egg composition, offspring performance and carcass yield were evaluated. Pullets were fed a diet containing high ME (2,736 kcal/kg; HEREAR), or low ME (2,528 kcal/kg; LEREAR) combined...
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Fall 2013
Protein adsorption at the biomaterial-tissue interface has several detrimental consequences which undermines the widespread application of engineered materials. Herein, it was asked what role protein secondary structures play in the adsorption of peptides, as well as how these structures affect...
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Elevation of global O-GlcNAc levels in 3T3-L1 adipocytes by selective inhibition of O-GlcNAcase does not induce insulin resistance
Download2008
Bubb, Abigail K., Macauley, Matthew S., Davies, Gideon J., Vocadlo, David J. , Martinez-Fleites, Carlos
The O-GlcNAc post-translational modification is considered to act as a sensor of nutrient flux through the hexosamine biosynthetic pathway. A cornerstone of this hypothesis is that global elevation of protein O-GlcNAc levels, typically induced with the non-selective O-GlcNAcase inhibitor PUGNAc...
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Energy use by the mountain pine beetle (Coleoptera: Curculionidae: Scolytinae) for dispersal by flight
Download2019-01-01
Wijerathna, Asha, Evenden, Maya
The mountain pine beetle, Dendroctonus ponderosae Hopkins is a major native pest of pine (Pinus Linnaeus (Pinaceae)) in western North America. Host colonization by mountain pine beetle is associated with an obligatory dispersal phase, during which beetles fly in search of a suitable host....
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Fall 2015
Tumor targeting ligands provide a promising solution to the problems associated with the selective delivery of conventional cancer chemotherapeutics and diagnostics to cancer cells. Therefore, numerous cancer cell surface targeting peptides have been identified and evaluated. These peptides have...
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Spring 2016
Peptides have a host of beneficial physiological effects and are often considered for therapeutic application to treat disease. However, poor bioavailabilities, problems with administration, sensitivity to environmental factors, and susceptibility to proteases limit them. The work presented in...
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Evaluation of Phosphatidylserine-Binding Peptides Radiolabeled with Fluorine 18 for in vivo Imaging of Apoptosis
DownloadSpring 2012
We currently do not have a clinical method to directly assess apoptosis induced by cancer therapies. Phosphatidylserine (PS) is an attractive target for imaging apoptosis since it is on the exterior of the apoptotic cells and PS externalization is an early marker of apoptosis. PS-binding peptides...
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1999
Tenniswood, M., Bennett, S., Wong, P., Morrissey, C., Nitsche, E., Guenette, R.S.
After hormonal ablation, 90% of the secretory epithelial cells of the prostate undergo apoptosis, and the remaining cells are reorganized as the tissue is remodeled. Using differential display RT-PCR of total RNA extracted from the rat ventral prostate before and 4 days after castration, we have...
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Expression of PPARα modifies fatty acid effects on insulin secretion in uncoupling protein-2 knockout mice
Download2007
Fatehi-Hassanabad, Zahra, Chan, Catherine B.
Aims/hypothesis In uncoupling protein-2 (UCP2) knockout (KO) mice, protection of beta cells from fatty acid exposure is dependent upon transcriptional events mediated by peroxisome proliferator-activated receptor-α (PPARα). Methods PPARα expression was reduced in isolated islets from UCP2KO and...