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Skip to Search Results- 5Fliegel, Larry
- 5Sykes, Brian D.
- 4Chamot, Danuta
- 4Owttrim, George W.
- 3Li, Xiuju J.
- 3Owttrim, George W.
- 18Graduate and Postdoctoral Studies (GPS), Faculty of
- 18Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 9Biological Sciences, Department of
- 9Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 5Biochemistry, Department of
- 5Biochemistry, Department of/Journal Articles (Biochemistry)
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Fall 2013
Protein adsorption at the biomaterial-tissue interface has several detrimental consequences which undermines the widespread application of engineered materials. Herein, it was asked what role protein secondary structures play in the adsorption of peptides, as well as how these structures affect...
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Fall 2015
Tumor targeting ligands provide a promising solution to the problems associated with the selective delivery of conventional cancer chemotherapeutics and diagnostics to cancer cells. Therefore, numerous cancer cell surface targeting peptides have been identified and evaluated. These peptides have...
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Spring 2016
Peptides have a host of beneficial physiological effects and are often considered for therapeutic application to treat disease. However, poor bioavailabilities, problems with administration, sensitivity to environmental factors, and susceptibility to proteases limit them. The work presented in...
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Evaluation of Phosphatidylserine-Binding Peptides Radiolabeled with Fluorine 18 for in vivo Imaging of Apoptosis
DownloadSpring 2012
We currently do not have a clinical method to directly assess apoptosis induced by cancer therapies. Phosphatidylserine (PS) is an attractive target for imaging apoptosis since it is on the exterior of the apoptotic cells and PS externalization is an early marker of apoptosis. PS-binding peptides...
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Spring 2016
Biomining is an efficient way for improving mineral extraction and remediation processes. Using specific/targeted separation is a promising method to increase purification yield of minerals and metals at low cost. In traditional methods extraction and purification of the desired materials from...
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Light Responsive Linchpins for Accelerated Discovery of Light-Responsive Mono- and Bicyclic Peptide Ligands
DownloadSpring 2016
In this thesis I describe the development and application of light-responsive (LR) linchpins for efficient discovery of LR-peptides from genetically encoded peptide librar-ies. LR-linchpins have been used for dynamic control of the structure of peptides and their biochemical properties such as...
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2017-01-01
Carvalho, Wildemar S. P., Wei, Menglian, Ikpo, Nduka, Gao, Yongfeng, Serpe, Michael J.
Reports in the literature on the development of new chemical sensing technologies have been growing steadily in number for years. For example, a Web of Science topic search using the term “Chemical Sensing” revealed that over 8 000 papers were published in 2015–2017, with over 40 000 citations to...