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Skip to Search Results- 37Graduate and Postdoctoral Studies (GPS), Faculty of
- 37Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 4Biological Sciences, Department of
- 4Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 4Biochemistry, Department of
- 4Biochemistry, Department of/Journal Articles (Biochemistry)
- 12Department of Chemistry
- 9Department of Agricultural, Food, and Nutritional Science
- 3Department of Food Science
- 3Faculty of Pharmacy and Pharmaceutical Sciences
- 2Department of Agricultural, Food and Nutritional Science
- 2Department of Chemical and Materials Engineering
- 5Vederas, John (Chemistry)
- 4McMullen, Lynn (Agricultural, Food and Nutritional Science)
- 3Vederas, John C. (Chemistry)
- 2Unsworth, Larry (Chemical and Materials Engineering)
- 1Bressler, David (Agricultural, Food, and Nutritional Science)
- 1Bressler, David (Department of Agricultural, Food and Nutritional Science)
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Control of Listeria monocytogenes and Heat-Resistant Escherichia coli on Vacuum-Packaged Beef
DownloadSpring 2012
Novel methods to control Listeria monocytogenes and Escherichia coli on vacuum-packaged raw beef were investigated. Bacteriocin-negative Lactobacillus sakei FUA3058 and bacteriocin-positive Carnobacterium maltaromaticum UAL307 were tested as biopreservatives, alone or in combination with...
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Design, Synthesis and Evaluation of Cancer Targeting α-Peptides and Novel Peptidomimetic β-Peptides
DownloadFall 2010
Current cancer therapies have low specificity for tumor cells and have serious toxic side effects. Targeting drugs to the cancer cells can help improve the outcome of existing cancer therapies. In recent years, a number of peptides have been identified by peptide phage display for targeting...
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Development and Application of Protected Amino Acids for the Installation of Stable Post-translational Modifications Using Solid-Phase Peptide Synthesis
DownloadFall 2022
This thesis describes the synthesis of non-canonical amino acid building blocks and their use in solid-phase peptide synthesis (SPPS) to explore peptidic drug analogues based on natural products. We replaced sensitive functionalities found in the structure of naturally produced peptides with...
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Fall 2015
Contamination by lactic acid bacteria is a major source of inefficiency in the bioethanol industry. Contaminated fermentations exhibit lowered ethanol yields and contamination events often require shutdown of the entire process for cleaning and decontamination. The first objective of this study...
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Development of polymer and lipid based nano-delivery systems for targeted cancer chemotherapy
DownloadFall 2012
Conventional chemotherapy agents can kill tumor cells and inhibit tumor growth, but they produce severe side effects on normal cells at the same time. To shift the balance towards tumoral effects, it would be desirable to direct the anti-cancer drug towards tumor while restricting drug access to...
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Divergent genes for translation inition factor elF-4A are coordinately expressed in tobacco
Download1991
Kuhlemeir, Cris, Holfmann, Sylvia, Owtrim, George W.
Three cDNA clones coding for eukaryotic translation initiation factor 4A, elF-4A, were isolated from a Nicotiana plumbaginifolia root cDNA library by heterologous screening. The clones comprise two distinct gene classes as two clones are highly similar while the third is divergent. The genes...
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Fall 2013
Protein adsorption at the biomaterial-tissue interface has several detrimental consequences which undermines the widespread application of engineered materials. Herein, it was asked what role protein secondary structures play in the adsorption of peptides, as well as how these structures affect...
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Fall 2015
Tumor targeting ligands provide a promising solution to the problems associated with the selective delivery of conventional cancer chemotherapeutics and diagnostics to cancer cells. Therefore, numerous cancer cell surface targeting peptides have been identified and evaluated. These peptides have...
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Spring 2016
Peptides have a host of beneficial physiological effects and are often considered for therapeutic application to treat disease. However, poor bioavailabilities, problems with administration, sensitivity to environmental factors, and susceptibility to proteases limit them. The work presented in...