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Skip to Search Results- 26Graduate and Postdoctoral Studies (GPS), Faculty of
- 26Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 20Nursing, Faculty of
- 10Nursing, Faculty of/Health Systems
- 9Nursing, Faculty of/Chronicity
- 9ACCES Research Group
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A pilot project examining the application of Multi-Modal Aphasia Treatment (M-MAT) in a long term care setting
Download2017-12-15
Chung, Angela, Mayo, Caroline, Cleary, Stuart, Kim, Esther
The purpose of this study is to examine: 1) the feasibility of adapting M-MAT to b delivered in a long term care setting and 2) the impact of adapted M-MAT on language and communication outcomes of an individual with aphasia.
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2013
Stewart, N., Morgan, D. G., Estabrooks, C. A., Norton, P., Squires, J. E., Poss, J. W., Doupe, M., Teare, G. F., Cummings, G. G.
Nursing homes have become complex care environments where residents have significant needs and most have age-related dementia. Building on research by Hirdes et al. (2011), we describe a resident profile in a representative sample of 30 urban nursing homes in the prairie provinces using Resident...
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Spring 2016
There is ample evidence that autophagy is affected in Alzheimer’s disease (AD) but the causes, the nature of the dysfunction and the mechanisms of autophagy impairment are unclear. Autophagy depends on vesicular trafficking and membrane fusion, events that rely on several protein complexes and...
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Fall 2019
Alzheimer’s disease (AD) is characterized by the accumulation of amyloid beta (Aβ) peptide. It has been proposed that AD pathology is transmissible by a “prion-like” mechanism through extracellular vesicles (EVs) that contain Aβ. In this context, EVs describe both microvesicles and exosomes,...
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Care Aides’ Perceptions and Experiences of their Roles and Relationships with Residents in Long-term Care Settings
DownloadFall 2012
The purpose of this study was to explore care aides’ perceptions and experiences of their roles and relationships with residents in long-term care institutions, and how the context, including the organizational philosophy, influenced those perceptions and experiences. The method of exploration...
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Cellular level/distribution of γ-secretase subunit nicastrin and its modulator p23 in the brain
DownloadSpring 2010
The processing of amyloid precursor protein (APP) by β- and γ-secretases produces amyloid β (Aβ) peptide, the principal component of the neuritic plaques found in Alzheimer’s disease (AD) pathology. The enzyme γ-secretase is a multimeric protein consisting of presenilins-1/2 (PS1/PS2), nicastrin,...
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Spring 2013
Alzheimer’s disease (AD) is a complex neurodegenerative disorder believed to be triggered by the accumulation of β-amyloid (Aβ)-related peptides derived from the proteolytic processing of amyloid precursor protein (APP). Research over the last two decades has shown that alterations in the levels...