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Fall 2018
Detection of biomolecules that are over- or under-expressed in diseases is an important field for early diagnosis, monitoring treatment, and improving patient prognosis. The main goal of my thesis is to utilize DNA nanotechnology combined with nanomaterials to provide sensitive and specific...
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Fall 2013
The discovery of green fluorescent protein (GFP) from the Aequorea victoria Jellyfish followed by the extensive efforts of protein engineers to produce other fluorescent proteins (FPs) spanning the visible color spectrum made fluorescent proteins indispensable biochemical tools in the scientific...
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Engineering a Chromoprotein Optimized for Photoacoustic Imaging and Biosensing Applications
DownloadFall 2014
A subset of the family of fluorescent proteins are the non-fluorescent chromoproteins which serve as important tools in biomedical research. Recently, chromoproteins have been utilized as both reporter molecules in photoacoustic imaging and acceptor chromophores in Förster resonance energy...
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Spring 2015
Supramolecular rosette nanotubes (RNTs) are obtained by the hierarchical self-assembly of mono and twin G^C building blocks. The mono G^C motif is a fused bicyclic ring of guanine and cytosine with six self-complementary sets of hydrogen bonding sites, while the twin G^C motif is a covalently...
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Fall 2013
Rosette nanotubes (RNTs) are bio-inspired nanomaterials generated from the self-assembly of a guanine-cytosine motif called the “G∧C” base. These nanotubular architectures are promising 2-D coating materials for bone tissue engineering applications, and delivery scaffolds for hydrophobic drug...